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APG5L Antibody, ALEXA FLUOR 594

APG5L Antibody, ALEXA FLUOR 594 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 594 Conjugated, APG5L Polyclonal Antibody
Also known asAnti-APG5L PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAPG5L
SpecificityThis is a highly specific antibody against APG5L
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range118-158/275
Subcellular location Membrane bound, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APG5L
Gene ID Number9474
Swiss ProtQ9H1Y0
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Also plays a role in translation or delivery of incoming viral RNA to the translation apparatus, Conjugation with ATG12, Involved in mitochondrial quality control after oxidative damage, Involved in the maintenance of axon morphology and membrane structures, Its expression is a relatively late event in the apoptotic process, May play an important role in the apoptotic process, Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation, Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD, Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT2 via the autophagic pathway, Required for optimal processing and presentation of antigens for MHC II, The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes, The ATG12-ATG5 conjugate also negatively regulates the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS, and in subsequent cellular longevity, as well as in normal adipocyte differentiation, is essential for its function, occurring downstream of caspase activity, possibly within the modified cytoskeleton, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG1 as an E2-like conjugating enzyme, Involved in autophagic vesicle formation
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms ASP APG5 hAPG5
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetAPG5L
Short nameAPG5L Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, APG5L (Antibody to)
Alternative techniqueantibodies
Identity 589
Gene ATG5
Long gene name autophagy related 5
Synonyms gene APG5L
Synonyms gene name APG5 (autophagy 5, S, cerevisiae) , cerevisiae) ATG5 autophagy related 5 homolog (S, cerevisiae)-like APG5 autophagy 5-like (S
Locus 6q21
Discovery year 1999-09-16
GenBank acession Y11588
Entrez gene record 9474
Pubmed identfication 9563500 11349150 15778222
RefSeq identity NM_004849
Classification Autophagy related
Havana BLAST/BLAT OTTHUMG00000016193

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