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APG5L Antibody, Cy7 Conjugated

APG5L Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, APG5L Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAPG5L
SpecificityThis is a highly specific antibody against APG5L
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range118-158/275
Subcellular location Membrane bound, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human APG5L
Gene ID number9474
Swiss ProtQ9H1Y0
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Also plays a role in translation or delivery of incoming viral RNA to the translation apparatus, Conjugation with ATG12, Involved in mitochondrial quality control after oxidative damage, Involved in the maintenance of axon morphology and membrane structures, Its expression is a relatively late event in the apoptotic process, May play an important role in the apoptotic process, Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation, Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD, Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT2 via the autophagic pathway, Required for optimal processing and presentation of antigens for MHC II, The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes, The ATG12-ATG5 conjugate also negatively regulates the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS, and in subsequent cellular longevity, as well as in normal adipocyte differentiation, is essential for its function, occurring downstream of caspase activity, possibly within the modified cytoskeleton, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG1 as an E2-like conjugating enzyme, Involved in autophagic vesicle formation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms ASP APG5 hAPG5
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetAPG5L Conjugated
Short name Conjugated, APG5L Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, APG5L (Antibody to)
Alternative techniqueantibodies
Identity 589
Gene ATG5
Long gene name autophagy related 5
Synonyms gene APG5L
Synonyms gene name APG5 (autophagy 5, S, cerevisiae) , cerevisiae) ATG5 autophagy related 5 homolog (S, cerevisiae)-like APG5 autophagy 5-like (S
Locus 6q21
Discovery year 1999-09-16
GenBank acession Y11588
Entrez gene record 9474
Pubmed identfication 9563500 11349150 15778222
RefSeq identity NM_004849
Classification Autophagy related
Havana BLAST/BLAT OTTHUMG00000016193

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