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APG7 Antibody

APG7 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameAPG7 Primary Polyclonal Antibody
Also known asAPG7 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenAPG7
SpecificityThis is a highly specific antibody against APG7
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range1-50/70
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ATG7
Gene ID number10533
Swiss ProtO95352
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine, Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes, Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress, Plays also a key role in the maintenance of axonal homeostasis, Required for autophagic death induced by caspase-8 inhibition, Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production, as well as in adipose differentiation, the formation of Paneth cell granules, the maintenance of hematopoietic stem cells, the prevention of axonal degeneration, E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names APG7-LIKE, APG7L, ATG12-activating enzyme E1 ATG7, ATG7, Autophagy-related protein 7, Ubiquitin-activating enzyme E1-like protein, Ubiquitin-like modifier-activating enzyme ATG7, hAGP7, GSA7
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetAPG7
Short nameAPG7 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameAPG7 (Antibody to)
Alternative techniqueantibodies
Identity 16935
Gene ATG7
Long gene name autophagy related 7
Synonyms gene APG7L
Synonyms gene name APG7 autophagy 7-like (S, cerevisiae) , cerevisiae) ATG7 autophagy related 7 homolog (S
Synonyms GSA7 DKFZp434N0735
Synonyms name ubiquitin-activating enzyme E1-like protein
Locus 3p25, 3
Discovery year 2003-11-20
GenBank acession AF094516
Entrez gene record 10533
Pubmed identfication 10233149
RefSeq identity NM_006395
Classification Ubiquitin like modifier activating enzymes Autophagy related
Havana BLAST/BLAT OTTHUMG00000129740

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