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APG7 Antibody, ALEXA FLUOR 594

APG7 Antibody, ALEXA FLUOR 594 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 594 Conjugated, APG7 Polyclonal Antibody
Also known asAnti-APG7 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAPG7
SpecificityThis is a highly specific antibody against APG7
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range1-50/70
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ATG7
Gene ID Number10533
Swiss ProtO95352
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine, Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes, Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress, Plays also a key role in the maintenance of axonal homeostasis, Required for autophagic death induced by caspase-8 inhibition, Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production, as well as in adipose differentiation, the formation of Paneth cell granules, the maintenance of hematopoietic stem cells, the prevention of axonal degeneration, E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms GSA7 DKFZp434N0735
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetAPG7
Short nameAPG7 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, APG7 (Antibody to)
Alternative techniqueantibodies
Identity 16935
Gene ATG7
Long gene name autophagy related 7
Synonyms gene APG7L
Synonyms gene name APG7 autophagy 7-like (S, cerevisiae) , cerevisiae) ATG7 autophagy related 7 homolog (S
Synonyms name ubiquitin-activating enzyme E1-like protein
Locus 3p25, 3
Discovery year 2003-11-20
GenBank acession AF094516
Entrez gene record 10533
Pubmed identfication 10233149
RefSeq identity NM_006395
Classification Ubiquitin like modifier activating enzymes Autophagy related
Havana BLAST/BLAT OTTHUMG00000129740

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