Name : Aph-1b Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN7644964652
| Long name | ALEXA FLUOR 488 Conjugated, Aph-1b Polyclonal Antibody |
| Also known as | Anti-Aph-1b PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Aph-1b |
| Specificity | This is a highly specific antibody against Aph-1b |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 75-125/257 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Aph-1b |
| Gene ID Number | 83464 |
| Swiss Prot | Q8WW43 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex, Probably present in a minority of gamma-secretase complexes compared to APH1A, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein), Probable subunit of the gamma-secretase complex |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | PSFL APH-1B DKFZp564D0372 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Aph-1b Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | Aph-1b |
| Short name | Aph-1b Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, Aph-1b (Antibody to) |
| Alternative technique | antibodies |
| Identity | 24080 |
| Gene | APH1B |
| Long gene name | aph-1 homolog B, gamma-secretase subunit |
| Synonyms gene name | anterior pharynx defective 1 homolog B (C, elegans) APH1B gamma secretase subunit |
| Locus | 15q22, 2 |
| Discovery year | 2005-02-08 |
| GenBank acession | AY358698 |
| Entrez gene record | 83464 |
| Pubmed identfication | 12110170 11230166 |
| RefSeq identity | NM_031301 |
| Havana BLAST/BLAT | OTTHUMG00000132863 |