Name : APLF Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN6520673862
| Long name | APLF Primary Polyclonal Antibody |
| Also known as | APLF PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | APLF |
| Specificity | This is a highly specific antibody against APLF |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APLF |
| Gene ID number | 200558 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | APLF interacts with XRCC1, APLF is subject to post-translational phosphorylation in response to DNA breaks, Additionally, Harlequin icthyosis, Localized to both the nucleus and the cytoplasm, The gene encoding APLF maps to human chromosome 2, XRCC4 and Ku-86 and, a rare and morbid skin deformity, an extremely rare recessive genetic disorder, is associated with mutations in the ABCA12 gene, is caused by mutations in the ALMS1 gene, is involved in single-strand and double-strand DNA break repair, via these interactions, which houses over 1, which maps to chromosome 2, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes, 400 genes and comprises nearly 8% of the human genome, APLF is a 511 amino acid protein that contains one FHA doman and two C2H2type zinc fingers |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | AI452191, APLF_HUMAN, Aplf, Aprataxin and pnk-like factor, Apurinic-apyrimidinic endonuclease APLF, C2orf13, PNK and APTX like FHA protein, PNK and APTX-like FHA domain-containing protein, RGD1565557, XIP1, XRCC1 interacting protein 1, XRCC1-interacting protein 1, 2010301N04Rik |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | APLF |
| Short name | APLF Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | APLF (Antibody to) |
| Alternative technique | antibodies |
| Identity | 28724 |
| Gene | APLF |
| Long gene name | aprataxin and PNKP like factor |
| Synonyms gene | C2orf13 |
| Synonyms gene name | chromosome 2 open reading frame 13 |
| Synonyms | MGC47799 Xip1 ZCCHH1 |
| Synonyms name | CX5CX6HX5H motif containing 1 , XRCC1-interacting protein 1 zinc finger |
| Locus | 2p13, 3 |
| Discovery year | 2004-01-09 |
| GenBank acession | BC030711 |
| Entrez gene record | 200558 |
| Pubmed identfication | 18474613 18077224 17353262 |
| RefSeq identity | NM_173545 |
| Classification | Zinc fingers |
| Havana BLAST/BLAT | OTTHUMG00000129566 |