| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | APOA1 / Apolipoprotein A I |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Rat |
| Tested applications | IHC-P, WB |
| Recommended dilutions | 1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes | Optimal dilution of the Apolipoprotein A I antibody should be determined by the researcher |
| Intented use | This Apolipoprotein A I antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P04639 |
| Purity | Antigen affinity |
| Description | Additionally, And it is a single polypeptide chain with 243 amino acid residues of known primary amino acid sequence, ApoA-I is also isolated as a prostacyclin (PGI2) stabilizing factor, ApoA-I overexpression promotes macrophage-specific reverse cholesterol transport, Defects in the gene encoding it are associated with HDL deficiencies, It binds to lipopolysaccharide or endotoxin, It is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters, The ApoA-I protein promotes cholesterol efflux from tissues to the liver for excretion, The gene is mapped to 11q23, also known as APOA1, and has a major role in the anti-endotoxin function of HDL, and thus may have an anticlotting effect, and with systemic non-neuropathic amyloidosis, including Tangier disease, is a human protein with a specific role in lipid metabolism, Apolipoprotein A-1 |
| Immunogen | Amino acids 25-259 of rat Apolipoprotein A I were used as the immunogen for the Apolipoprotein A I antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Apolipoprotein A I antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization | membranous, Cytoplasmic |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | APOA1 / Apolipoprotein A I |
| Short name | APOA1 Antibody / Apolipoprotein A I |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | apolipoprotein A-I (Antibody to) / Apolipoprotein A I |
| Alternative technique | antibodies |
| Alternative to gene target | APOA1 and IDBG-630796 and ENSBTAG00000002258 and 281631, APOA1 and IDBG-72644 and ENSG00000118137 and 335, Apoa1 and IDBG-161189 and ENSMUSG00000032083 and 11806, lipoprotein particle binding, nuclei, this GO :0001523 and retinoid metabolic process and biological process this GO :0001540 and beta-amyloid binding and molecular function this GO :0001932 and regulation of protein phosphorylation and biological process this GO :0001935 and endothelial cell proliferation and biological process this GO :0002576 and platelet degranulation and biological process this GO :0002740 and negative regulation of cytokine secretion involved in immune response and biological process this GO :0005319 and lipid transporter activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005543 and phospholipid binding and molecular function this GO :0005548 and phospholipid transporter activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005769 and early endosome and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006644 and phospholipid metabolic process and biological process this GO :0006656 and phosphatidylcholine biosynthetic process and biological process this GO :0006695 and cholesterol biosynthetic process and biological process this GO :0006869 and lipid transport and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007584 and response to nutrient and biological process this GO :0007596 and blood coagulation and biological process this GO :0007603 and phototransduction, this GO :0001540: beta-amyloid binding, this GO :0001540: beta-amyloid binding and also this GO :0005319: lipid transporter activity and also this GO :0005515: protein binding and also this GO :0005543: phospholipid binding and also this GO :0005548: phospholipid transporter activity and also this GO :0008035: high-density lipoprotein particle binding and also this GO :0008289: lipid binding and also this GO :0015485: cholesterol binding and also this GO :0017127: cholesterol transporter activity and also this GO :0019899: enzyme binding and also this GO :0034190: apolipoprotein receptor binding and also this GO :0034191: apolipoprotein A-I receptor binding and also this GO :0042802: identical protein binding and also this GO :0055102: lipase inhibitor activity and also this GO :0060228: phosphatidylcholine-sterol O-acyltransferase activator activity and also this GO :0070653: high-density lipoprotein particle receptor binding and also this GO :0071813: lipoprotein particle binding, this GO :0005319: lipid transporter activity, this GO :0005515: protein binding, this GO :0005543: phospholipid binding, this GO :0005548: phospholipid transporter activity, this GO :0008035: high-density lipoprotein particle binding, this GO :0008289: lipid binding, this GO :0015485: cholesterol binding, this GO :0017127: cholesterol transporter activity, this GO :0019899: enzyme binding, this GO :0034190: apolipoprotein receptor binding, this GO :0034191: apolipoprotein A-I receptor binding, this GO :0042802: identical protein binding, this GO :0055102: lipase inhibitor activity, this GO :0060228: phosphatidylcholine-sterol O-acyltransferase activator activity, this GO :0070653: high-density lipoprotein particle receptor binding, this GO :0071813: lipoprotein particle binding, visible light and biological process this GO :0008035 and high-density lipoprotein particle binding and molecular function this GO :0008203 and cholesterol metabolic process and biological process this GO :0008211 and glucocorticoid metabolic process and biological process this GO :0008289 and lipid binding and molecular function this GO :0009986 and cell surface and cellular component this GO :0010804 and negative regulation of tumor necrosis factor-mediated signaling pathway and biological process this GO :0010873 and positive regulation of cholesterol esterification and biological process this GO :0010903 and negative regulation of very-low-density lipoprotein particle remodeling and biological process this GO :0014012 and peripheral nervous system axon regeneration and biological process this GO :0015485 and cholesterol binding and molecular function this GO :0015914 and phospholipid transport and biological process this GO :0017127 and cholesterol transporter activity and molecular function this GO :0018158 and protein oxidation and biological process this GO :0018206 and peptidyl-methionine modification and biological process this GO :0019899 and enzyme binding and molecular function this GO :0019915 and lipid storage and biological process this GO :0030139 and endocytic vesicle and cellular component this GO :0030168 and platelet activation and biological process this GO :0030300 and regulation of intestinal cholesterol absorption and biological process this GO :0030301 and cholesterol transport and biological process this GO :0030325 and adrenal gland development and biological process this GO :0031100 and organ regeneration and biological process this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0032489 and regulation of Cdc42 protein signal transduction and biological process this GO :0033344 and cholesterol efflux and biological process this GO :0033700 and phospholipid efflux and biological process this GO :0034115 and negative regulation of heterotypic cell-cell adhesion and biological process this GO :0034190 and apolipoprotein receptor binding and molecular function this GO :0034191 and apolipoprotein A-I receptor binding and molecular function this GO :0034361 and very-low-density lipoprotein particle and cellular component this GO :0034364 and high-density lipoprotein particle and cellular component this GO :0034365 and discoidal high-density lipoprotein particle and cellular component this GO :0034366 and spherical high-density lipoprotein particle and cellular component this GO :0034375 and high-density lipoprotein particle remodeling and biological process this GO :0034380 and high-density lipoprotein particle assembly and biological process this GO :0034384 and high-density lipoprotein particle clearance and biological process this GO :0034774 and secretory granule lumen and cellular component this GO :0042157 and lipoprotein metabolic process and biological process this GO :0042158 and lipoprotein biosynthetic process and biological process this GO :0042493 and response to drug and biological process this GO :0042632 and cholesterol homeostasis and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043534 and blood vessel endothelial cell migration and biological process this GO :0043627 and response to estrogen and biological process this GO :0043691 and reverse cholesterol transport and biological process this GO :0044255 and cellular lipid metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0050713 and negative regulation of interleukin-1 beta secretion and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0050821 and protein stabilization and biological process this GO :0051345 and positive regulation of hydrolase activity and biological process this GO :0051346 and negative regulation of hydrolase activity and biological process this GO :0051347 and positive regulation of transferase activity and biological process this GO :0055085 and transmembrane transport and biological process this GO :0055091 and phospholipid homeostasis and biological process this GO :0055102 and lipase inhibitor activity and molecular function this GO :0060192 and negative regulation of lipase activity and biological process this GO :0060228 and phosphatidylcholine-sterol O-acyltransferase activator activity and molecular function this GO :0060354 and negative regulation of cell adhesion molecule production and biological process this GO :0060761 and negative regulation of response to cytokine stimulus and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070328 and triglyceride homeostasis and biological process this GO :0070508 and cholesterol import and biological process this GO :0070653 and high-density lipoprotein particle receptor binding and molecular function this GO :0071682 and endocytic vesicle lumen and cellular component this GO :0071813 and lipoprotein particle binding and molecular function this GO :0072562 and blood microparticle and cellular component, apolipoprotein A-I |
| Identity | 600 |
| Gene | APOA1 |
| Long gene name | apolipoprotein A1 |
| Synonyms gene name | apolipoprotein A-I |
| Locus | 11q23, 3 |
| Discovery year | 2001-06-22 |
| GenBank acession | X02162 |
| Entrez gene record | 335 |
| RefSeq identity | NM_000039 |
| Classification | Apolipoproteins |
| Havana BLAST/BLAT | OTTHUMG00000046112 |
| Locus Specific Databases | LRG_767 |
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