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APOBEC3B Antibody, Biotin Conjugated

APOBEC3B Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, APOBEC3B Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAPOBEC3B
SpecificityThis is a highly specific antibody against APOBEC3B
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range20-60/382
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human APOBEC3B
Gene ID number9582
Swiss ProtQ9UH17
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, Exhibits antiviral activity against simian immunodeficiency virus (SIV), Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA, The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, hepatitis B virus (HBV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA, together exert efficient antiretroviral effects in infected target cells, DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms PHRBNL FLJ21201
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetAPOBEC3B Conjugated
Short name Conjugated, APOBEC3B Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, APOBEC3B (Antibody to)
Alternative techniqueantibodies
Identity 17352
Gene APOBEC3B
Long gene name apolipoprotein B mRNA editing enzyme catalytic subunit 3B
Synonyms gene name apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
Synonyms name phorbolin 3
Locus 22q13, 1
Discovery year 2001-12-12
GenBank acession AK024854
Entrez gene record 9582
Pubmed identfication 11863358 10469298
RefSeq identity NM_004900
Classification Apolipoprotein B mRNA editing enzyme catalytic subunits Minor histocompatibility antigens
Havana BLAST/BLAT OTTHUMG00000151085

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