Name : APOBEC3B Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN6168253760
| Long name | Biotin Conjugated, APOBEC3B Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | APOBEC3B |
| Specificity | This is a highly specific antibody against APOBEC3B |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 20-60/382 |
| Subcellular location | Nucleus |
| Source | KLH conjugated synthetic peptide derived from human APOBEC3B |
| Gene ID number | 9582 |
| Swiss Prot | Q9UH17 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, Exhibits antiviral activity against simian immunodeficiency virus (SIV), Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA, The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, hepatitis B virus (HBV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA, together exert efficient antiretroviral effects in infected target cells, DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | PHRBNL FLJ21201 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | APOBEC3B Conjugated |
| Short name | Conjugated, APOBEC3B Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, APOBEC3B (Antibody to) |
| Alternative technique | antibodies |
| Identity | 17352 |
| Gene | APOBEC3B |
| Long gene name | apolipoprotein B mRNA editing enzyme catalytic subunit 3B |
| Synonyms gene name | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| Synonyms name | phorbolin 3 |
| Locus | 22q13, 1 |
| Discovery year | 2001-12-12 |
| GenBank acession | AK024854 |
| Entrez gene record | 9582 |
| Pubmed identfication | 11863358 10469298 |
| RefSeq identity | NM_004900 |
| Classification | Apolipoprotein B mRNA editing enzyme catalytic subunits Minor histocompatibility antigens |
| Havana BLAST/BLAT | OTTHUMG00000151085 |