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APOBEC3C Antibody, ALEXA FLUOR 488

APOBEC3C Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, APOBEC3C Polyclonal Antibody
Also known asAnti-APOBEC3C PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAPOBEC3C
SpecificityThis is a highly specific antibody against APOBEC3C
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APOBEC3C
Gene ID Number27350
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen APOBEC3F deaminates deoxycytosine to deoxyuracil in the minus strand of HIV-1 DNA, APOBEC3G and APOBEC3F provide a mechanism for innate immunity to retroviruses, HIV-1 Vif cannot form a complex with APOBEC3G or APOBEC3F of mouse origin as it does with the human protein, Interestingly, Like APOBEC3G, The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22, This implies that induction of APOBEC3G and APOBEC3F activity or a method of blocking their interaction with Vif may provide a method for therapeutic intervention, Thus, Viral infectivity factor (Vif) imparts APOBEC3G and APOBEC3F resistance to HIV through impaired translation of their mRNA and accelerated posttranslational degradation of the APOBEC3 proteins by the 26S proteasome, and are also likely contribute to sequence variation observed in many viruses, and thus mouse APOBEC3G and APOBEC3F function as a potent inhibitors of wildtype HIV-1 replication, resulting in G to A hypermutation in the plus strand of DNA, where human APOBEC3G and APOBEC3F are only able to inhibit Vif-deficient HIV-1 replication, APOBEC proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms APOBEC1L PBI bK150C2, 3 ARDC2 ARDC4 ARP5
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the APOBEC3C Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetAPOBEC3C
Short nameAPOBEC3C Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, APOBEC3C (Antibody to)
Alternative techniqueantibodies
Identity 17353
Gene APOBEC3C
Long gene name apolipoprotein B mRNA editing enzyme catalytic subunit 3C
Synonyms gene name apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
Locus 22q13, 1
Discovery year 2001-12-12
GenBank acession AF165520
Entrez gene record 27350
Pubmed identfication 11863358
RefSeq identity NM_014508
Classification Apolipoprotein B mRNA editing enzyme catalytic subunits
Havana BLAST/BLAT OTTHUMG00000151087

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