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APOBEC3C Antibody, Cy5 Conjugated

APOBEC3C Antibody, Cy5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5 Conjugated, APOBEC3C Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAPOBEC3C
SpecificityThis is a highly specific antibody against APOBEC3C
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human APOBEC3C
Gene ID number27350
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background APOBEC3F deaminates deoxycytosine to deoxyuracil in the minus strand of HIV-1 DNA, APOBEC3G and APOBEC3F provide a mechanism for innate immunity to retroviruses, HIV-1 Vif cannot form a complex with APOBEC3G or APOBEC3F of mouse origin as it does with the human protein, Interestingly, Like APOBEC3G, The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22, This implies that induction of APOBEC3G and APOBEC3F activity or a method of blocking their interaction with Vif may provide a method for therapeutic intervention, Thus, Viral infectivity factor (Vif) imparts APOBEC3G and APOBEC3F resistance to HIV through impaired translation of their mRNA and accelerated posttranslational degradation of the APOBEC3 proteins by the 26S proteasome, and are also likely contribute to sequence variation observed in many viruses, and thus mouse APOBEC3G and APOBEC3F function as a potent inhibitors of wildtype HIV-1 replication, resulting in G to A hypermutation in the plus strand of DNA, where human APOBEC3G and APOBEC3F are only able to inhibit Vif-deficient HIV-1 replication, APOBEC proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Synonyms APOBEC1L PBI bK150C2, 3 ARDC2 ARDC4 ARP5
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetAPOBEC3C Conjugated
Short name Conjugated, APOBEC3C Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name cyanine 5 coupled, APOBEC3C (Antibody to)
Alternative techniqueantibodies
Identity 17353
Gene APOBEC3C
Long gene name apolipoprotein B mRNA editing enzyme catalytic subunit 3C
Synonyms gene name apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
Locus 22q13, 1
Discovery year 2001-12-12
GenBank acession AF165520
Entrez gene record 27350
Pubmed identfication 11863358
RefSeq identity NM_014508
Classification Apolipoprotein B mRNA editing enzyme catalytic subunits
Havana BLAST/BLAT OTTHUMG00000151087

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