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APOC3 Antibody / Apolipoprotein C III

APOC3 Antibody / Apolipoprotein C III size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenAPOC3 / Apolipoprotein C III
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus)
Tested applicationsWB
Recommended dilutions5-1ug/ml, Western blot: 0
Added buffer025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2
Intented useThis APOC3 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P02656
PurityAntigen affinity
Description APOC3 and APOA4 genes are closely linked in both rat and human genomes, APOC3 inhibits lipoprotein lipase and hepatic lipase, An increase in apoC-III levels induces the development of hypertriglyceridemia, Apo-CIII is a component of very low density lipoprotein (VLDL), The A-I and A-IV genes are transcribed from the same strand, The APOA1, also known as apo-CIII, is a protein that in humans is encoded by the APOC3 gene, it is thought to delay catabolism of triglyceride-rich particles, while the A-1 and C-III genes are convergently transcribed, Apolipoprotein C-III
ImmunogenAmino acids S21-A99 from the human protein were used as the immunogen for the APOC3 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the APOC3 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetAPOC3 / Apolipoprotein C III
Short nameAPOC3 Antibody / Apolipoprotein C III
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameapolipoprotein C-III (Antibody to) / Apolipoprotein C III
Alternative techniqueantibodies
Alternative to gene target APOC3 and IDBG-630792 and ENSBTAG00000012398 and 408009, APOC3 and IDBG-72562 and ENSG00000110245 and 345, APOCIII and HALP2, Apoc3 and IDBG-161220 and ENSMUSG00000032081 and 11814, Extracellular, high-density lipoprotein particle receptor binding, this GO :0001523 and retinoid metabolic process and biological process this GO :0005543 and phospholipid binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005769 and early endosome and cellular component this GO :0006641 and triglyceride metabolic process and biological process this GO :0006642 and triglyceride mobilization and biological process this GO :0006869 and lipid transport and biological process this GO :0006954 and inflammatory response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007584 and response to nutrient and biological process this GO :0007603 and phototransduction, this GO :0005543: phospholipid binding, this GO :0005543: phospholipid binding and also this GO :0008289: lipid binding and also this GO :0015485: cholesterol binding and also this GO :0030234: enzyme regulator activity and also this GO :0055102: lipase inhibitor activity and also this GO :0070653: high-density lipoprotein particle receptor binding, this GO :0008289: lipid binding, this GO :0015485: cholesterol binding, this GO :0030234: enzyme regulator activity, this GO :0055102: lipase inhibitor activity, this GO :0070653: high-density lipoprotein particle receptor binding, visible light and biological process this GO :0008203 and cholesterol metabolic process and biological process this GO :0008289 and lipid binding and molecular function this GO :0010897 and negative regulation of triglyceride catabolic process and biological process this GO :0010903 and negative regulation of very-low-density lipoprotein particle remodeling and biological process this GO :0010916 and negative regulation of very-low-density lipoprotein particle clearance and biological process this GO :0010987 and negative regulation of high-density lipoprotein particle clearance and biological process this GO :0010989 and negative regulation of low-density lipoprotein particle clearance and biological process this GO :0015485 and cholesterol binding and molecular function this GO :0019433 and triglyceride catabolic process and biological process this GO :0030234 and enzyme regulator activity and molecular function this GO :0032489 and regulation of Cdc42 protein signal transduction and biological process this GO :0033344 and cholesterol efflux and biological process this GO :0033700 and phospholipid efflux and biological process this GO :0034361 and very-low-density lipoprotein particle and cellular component this GO :0034363 and intermediate-density lipoprotein particle and cellular component this GO :0034366 and spherical high-density lipoprotein particle and cellular component this GO :0034375 and high-density lipoprotein particle remodeling and biological process this GO :0034379 and very-low-density lipoprotein particle assembly and biological process this GO :0034382 and chylomicron remnant clearance and biological process this GO :0042157 and lipoprotein metabolic process and biological process this GO :0042493 and response to drug and biological process this GO :0042627 and chylomicron and cellular component this GO :0042632 and cholesterol homeostasis and biological process this GO :0042953 and lipoprotein transport and biological process this GO :0043434 and response to peptide hormone and biological process this GO :0043691 and reverse cholesterol transport and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045717 and negative regulation of fatty acid biosynthetic process and biological process this GO :0045833 and negative regulation of lipid metabolic process and biological process this GO :0048261 and negative regulation of receptor-mediated endocytosis and biological process this GO :0050995 and negative regulation of lipid catabolic process and biological process this GO :0051005 and negative regulation of lipoprotein lipase activity and biological process this GO :0055102 and lipase inhibitor activity and molecular function this GO :0060621 and negative regulation of cholesterol import and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070328 and triglyceride homeostasis and biological process this GO :0070653 and high-density lipoprotein particle receptor binding and molecular function this GO :0071333 and cellular response to glucose stimulus and biological process, apolipoprotein C-III
Identity 610
Gene APOC3
Long gene name apolipoprotein C3
Synonyms gene name apolipoprotein C-III
Locus 11q23, 3
Discovery year 2001-06-22
GenBank acession X01388
Entrez gene record 345
RefSeq identity NM_000040
Classification Apolipoproteins
Havana BLAST/BLAT OTTHUMG00000046115

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