Name : APOC3 Antibody / Apolipoprotein C III
Supplier : NJS POLY
Price :406
SKU : GEN5414081720
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | APOC3 / Apolipoprotein C III |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications | WB |
| Recommended dilutions | 5-1ug/ml, Western blot: 0 |
| Added buffer | 025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2 |
| Intented use | This APOC3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P02656 |
| Purity | Antigen affinity |
| Description | APOC3 and APOA4 genes are closely linked in both rat and human genomes, APOC3 inhibits lipoprotein lipase and hepatic lipase, An increase in apoC-III levels induces the development of hypertriglyceridemia, Apo-CIII is a component of very low density lipoprotein (VLDL), The A-I and A-IV genes are transcribed from the same strand, The APOA1, also known as apo-CIII, is a protein that in humans is encoded by the APOC3 gene, it is thought to delay catabolism of triglyceride-rich particles, while the A-1 and C-III genes are convergently transcribed, Apolipoprotein C-III |
| Immunogen | Amino acids S21-A99 from the human protein were used as the immunogen for the APOC3 antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the APOC3 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | APOC3 / Apolipoprotein C III |
| Short name | APOC3 Antibody / Apolipoprotein C III |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | apolipoprotein C-III (Antibody to) / Apolipoprotein C III |
| Alternative technique | antibodies |
| Alternative to gene target | APOC3 and IDBG-630792 and ENSBTAG00000012398 and 408009, APOC3 and IDBG-72562 and ENSG00000110245 and 345, APOCIII and HALP2, Apoc3 and IDBG-161220 and ENSMUSG00000032081 and 11814, Extracellular, high-density lipoprotein particle receptor binding, this GO :0001523 and retinoid metabolic process and biological process this GO :0005543 and phospholipid binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005769 and early endosome and cellular component this GO :0006641 and triglyceride metabolic process and biological process this GO :0006642 and triglyceride mobilization and biological process this GO :0006869 and lipid transport and biological process this GO :0006954 and inflammatory response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007584 and response to nutrient and biological process this GO :0007603 and phototransduction, this GO :0005543: phospholipid binding, this GO :0005543: phospholipid binding and also this GO :0008289: lipid binding and also this GO :0015485: cholesterol binding and also this GO :0030234: enzyme regulator activity and also this GO :0055102: lipase inhibitor activity and also this GO :0070653: high-density lipoprotein particle receptor binding, this GO :0008289: lipid binding, this GO :0015485: cholesterol binding, this GO :0030234: enzyme regulator activity, this GO :0055102: lipase inhibitor activity, this GO :0070653: high-density lipoprotein particle receptor binding, visible light and biological process this GO :0008203 and cholesterol metabolic process and biological process this GO :0008289 and lipid binding and molecular function this GO :0010897 and negative regulation of triglyceride catabolic process and biological process this GO :0010903 and negative regulation of very-low-density lipoprotein particle remodeling and biological process this GO :0010916 and negative regulation of very-low-density lipoprotein particle clearance and biological process this GO :0010987 and negative regulation of high-density lipoprotein particle clearance and biological process this GO :0010989 and negative regulation of low-density lipoprotein particle clearance and biological process this GO :0015485 and cholesterol binding and molecular function this GO :0019433 and triglyceride catabolic process and biological process this GO :0030234 and enzyme regulator activity and molecular function this GO :0032489 and regulation of Cdc42 protein signal transduction and biological process this GO :0033344 and cholesterol efflux and biological process this GO :0033700 and phospholipid efflux and biological process this GO :0034361 and very-low-density lipoprotein particle and cellular component this GO :0034363 and intermediate-density lipoprotein particle and cellular component this GO :0034366 and spherical high-density lipoprotein particle and cellular component this GO :0034375 and high-density lipoprotein particle remodeling and biological process this GO :0034379 and very-low-density lipoprotein particle assembly and biological process this GO :0034382 and chylomicron remnant clearance and biological process this GO :0042157 and lipoprotein metabolic process and biological process this GO :0042493 and response to drug and biological process this GO :0042627 and chylomicron and cellular component this GO :0042632 and cholesterol homeostasis and biological process this GO :0042953 and lipoprotein transport and biological process this GO :0043434 and response to peptide hormone and biological process this GO :0043691 and reverse cholesterol transport and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045717 and negative regulation of fatty acid biosynthetic process and biological process this GO :0045833 and negative regulation of lipid metabolic process and biological process this GO :0048261 and negative regulation of receptor-mediated endocytosis and biological process this GO :0050995 and negative regulation of lipid catabolic process and biological process this GO :0051005 and negative regulation of lipoprotein lipase activity and biological process this GO :0055102 and lipase inhibitor activity and molecular function this GO :0060621 and negative regulation of cholesterol import and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070328 and triglyceride homeostasis and biological process this GO :0070653 and high-density lipoprotein particle receptor binding and molecular function this GO :0071333 and cellular response to glucose stimulus and biological process, apolipoprotein C-III |
| Identity | 610 |
| Gene | APOC3 |
| Long gene name | apolipoprotein C3 |
| Synonyms gene name | apolipoprotein C-III |
| Locus | 11q23, 3 |
| Discovery year | 2001-06-22 |
| GenBank acession | X01388 |
| Entrez gene record | 345 |
| RefSeq identity | NM_000040 |
| Classification | Apolipoproteins |
| Havana BLAST/BLAT | OTTHUMG00000046115 |