Filters

ApoER2 Antibody

ApoER2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameApoER2 Primary Polyclonal Antibody
Also known asApoER2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenApoER2
Specificity This antibody will detect both the membrane bound and the secreted isoform variants of this protein, This is a highly specific antibody against ApoER2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range848-898/963
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ApoER2
Gene ID number7804
Swiss ProtQ14114
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Binds dimers of beta 2-glycoprotein I and may be involved in the suppression of platelet aggregation in the vasculature, Binds the endoplasmic reticulum resident receptor-associated protein (RAP), Highly expressed in the initial segment of the epididymis, LRP8 has higher affinity for Reelin than VLDLR, LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brain development, LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, May also function as an endocytic receptor, Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons, by binding to DAB1 on its cytoplasmic tail, two proteins required for sperm maturation, where it affects the functional expression of clusterin and phospholipid hydroperoxide glutathione peroxidase (PHGPx), Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names APOER2, Apolipoprotein E receptor 2, HSZ75190, LRP-8, LRP8, Low-density lipoprotein receptor-related protein 8, MCI1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetApoER2
Short nameApoER2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameApoER2 (Antibody to)
Alternative techniqueantibodies
Identity 6700
Gene LRP8
Long gene name LDL receptor related protein 8
Synonyms gene name apolipoprotein e receptor , low density lipoprotein receptor-related protein 8
Synonyms APOER2 MCI1 LRP-8 HSZ75190
Locus 1p32, 3
Discovery year 1998-08-13
GenBank acession D50678
Entrez gene record 7804
Pubmed identfication 8626535 9079678
RefSeq identity NM_004631
Classification Low density lipoprotein receptors
Havana BLAST/BLAT OTTHUMG00000008924

Similar products

Subscribe to our Newsletter