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ApoER2 Antibody, ALEXA FLUOR 488

ApoER2 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, ApoER2 Polyclonal Antibody
Also known asAnti-ApoER2 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenApoER2
SpecificityThis is a highly specific antibody against ApoER2
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range848-898/963
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ApoER2
Gene ID Number7804
Swiss ProtQ14114
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Binds dimers of beta 2-glycoprotein I and may be involved in the suppression of platelet aggregation in the vasculature, Binds the endoplasmic reticulum resident receptor-associated protein (RAP), Highly expressed in the initial segment of the epididymis, LRP8 has higher affinity for Reelin than VLDLR, LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brain development, LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, May also function as an endocytic receptor, Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons, by binding to DAB1 on its cytoplasmic tail, two proteins required for sperm maturation, where it affects the functional expression of clusterin and phospholipid hydroperoxide glutathione peroxidase (PHGPx), Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms APOER2 MCI1 LRP-8 HSZ75190
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the ApoER2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetApoER2
Short nameApoER2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, ApoER2 (Antibody to)
Alternative techniqueantibodies
Identity 6700
Gene LRP8
Long gene name LDL receptor related protein 8
Synonyms gene name apolipoprotein e receptor , low density lipoprotein receptor-related protein 8
Locus 1p32, 3
Discovery year 1998-08-13
GenBank acession D50678
Entrez gene record 7804
Pubmed identfication 8626535 9079678
RefSeq identity NM_004631
Classification Low density lipoprotein receptors
Havana BLAST/BLAT OTTHUMG00000008924

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