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Apolipoprotein J Antibody

Apolipoprotein J Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameApolipoprotein J Primary Polyclonal Antibody
Also known asApolipoprotein J PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenApolipoprotein J
SpecificityThis is a highly specific antibody against Apolipoprotein J
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range433-442/449
Subcellular location Mitochondrion, Nucleus, Secreted, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Apolipoprotein J
Gene ID number1191
Swiss ProtP10909
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen APOC2, B2M, Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysosomal or proteasomal degradation, CALCA, CSN3, Does not refold proteins by itself, Does not require ATP, Inhibits formation of amyloid fibrils by APP, Intracellular isoforms interact with ubiquitin and SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes and promote the ubiquitination and subsequent proteasomal degradation of target proteins, Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, Mitochondrial isoforms suppress BAX-dependent release of cytochrome c into the cytoplasm and inhibit apoptosis, Modulates NF-kappa-B transcriptional activity, Nuclear isoforms promote apoptosis, Plays a role in the regulation of cell proliferation, Prevents stress-induced aggregation of blood plasma proteins, Promotes proteasomal degradation of COMMD1 and IKBKB, SNCA and aggregation-prone LYZ variants (in vitro), Secreted isoform 1 protects cells against apoptosis and against cytolysis by complement, such as HSPA8/HSC7, Isoform 1 functions as extracellular chaperone that prevents aggregation of nonnative proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names AAG4, APO-J, APOJ, Aging-associated gene 4 protein, Apolipoprotein J, CLU, CLU1, CLU2, Clusterin, Complement cytolysis inhibitor, Complement-associated protein SP-4, KUB1, Ku7-binding protein 1, NA1/NA2, SGP-2, SGP2, SP-4, TRPM-2, TRPM2, Testosterone-repressed prostate message 2, 4, CLI
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetApolipoprotein J
Short nameApolipoprotein J Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameApolipoprotein J (Antibody to)
Alternative techniqueantibodies
Identity 2061
Gene CLI
Long gene name clusterin
Synonyms gene APOJ
Synonyms gene name SP-40, apolipoprotein J) , clusterin (complement lysis inhibitor, sulfated glycoprotein 2, testosterone-repressed prostate message 2, 40
Synonyms SGP-2 SP-40 TRPM-2 KUB1 CLU1 CLU2 CLU
Synonyms name complement lysis inhibitor sulfated glycoprotein 2 testosterone-repressed prostate message 2 apolipoprotein J
Locus 8p21, 1
Discovery year 1990-07-26
GenBank acession M64722
Entrez gene record 1191
Pubmed identfication 1585460
RefSeq identity NM_001831
Havana BLAST/BLAT OTTHUMG00000102114

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