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APPBP1 Antibody

APPBP1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameAPPBP1 Primary Polyclonal Antibody
Also known asAPPBP1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenAPPBP1
SpecificityThis is a highly specific antibody against APPBP1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range440-490/534
Subcellular locationCell membrane
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APPBP1
Gene ID number8883
Swiss ProtQ13564
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M, Necessary for cell cycle progression through the S-M checkpoint, Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP, Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 59 kDa, A-116A10, APP-BP1, APPBP1, Amyloid beta precursor protein-binding protein 1, Amyloid protein-binding protein 1, NAE1, NEDD8-activating enzyme E1 regulatory subunit, Proto-oncogene protein 1, ula-1, 1, HPP1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetAPPBP1
Short nameAPPBP1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameAPPBP1 (Antibody to)
Alternative techniqueantibodies
Identity 621
Gene NAE1
Long gene name NEDD8 activating enzyme E1 subunit 1
Synonyms gene APPBP1
Synonyms gene name 59kDa , amyloid beta precursor protein binding protein 1
Synonyms ula-1 APP-BP1
Locus 16q22, 1
Discovery year 1999-01-13
GenBank acession U50939
Entrez gene record 8883
Pubmed identfication 8626687 12740388
RefSeq identity NM_003905
Classification Ubiquitin like modifier activating enzymes
Havana BLAST/BLAT OTTHUMG00000137513

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