Name : APPBP1 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN6597690865
| Long name | Biotin Conjugated, APPBP1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | APPBP1 |
| Specificity | This is a highly specific antibody against APPBP1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 440-490/534 |
| Subcellular location | Cell membrane |
| Source | KLH conjugated synthetic peptide derived from human APPBP1 |
| Gene ID number | 8883 |
| Swiss Prot | Q13564 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M, Necessary for cell cycle progression through the S-M checkpoint, Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP, Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | ula-1 APP-BP1 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | APPBP1 Conjugated |
| Short name | Conjugated, APPBP1 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, APPBP1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 621 |
| Gene | NAE1 |
| Long gene name | NEDD8 activating enzyme E1 subunit 1 |
| Synonyms gene | APPBP1 |
| Synonyms gene name | 59kDa , amyloid beta precursor protein binding protein 1 |
| Locus | 16q22, 1 |
| Discovery year | 1999-01-13 |
| GenBank acession | U50939 |
| Entrez gene record | 8883 |
| Pubmed identfication | 8626687 12740388 |
| RefSeq identity | NM_003905 |
| Classification | Ubiquitin like modifier activating enzymes |
| Havana BLAST/BLAT | OTTHUMG00000137513 |