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APPBP1 Antibody, Biotin Conjugated

APPBP1 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, APPBP1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAPPBP1
SpecificityThis is a highly specific antibody against APPBP1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range440-490/534
Subcellular locationCell membrane
SourceKLH conjugated synthetic peptide derived from human APPBP1
Gene ID number8883
Swiss ProtQ13564
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M, Necessary for cell cycle progression through the S-M checkpoint, Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP, Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms ula-1 APP-BP1
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetAPPBP1 Conjugated
Short name Conjugated, APPBP1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, APPBP1 (Antibody to)
Alternative techniqueantibodies
Identity 621
Gene NAE1
Long gene name NEDD8 activating enzyme E1 subunit 1
Synonyms gene APPBP1
Synonyms gene name 59kDa , amyloid beta precursor protein binding protein 1
Locus 16q22, 1
Discovery year 1999-01-13
GenBank acession U50939
Entrez gene record 8883
Pubmed identfication 8626687 12740388
RefSeq identity NM_003905
Classification Ubiquitin like modifier activating enzymes
Havana BLAST/BLAT OTTHUMG00000137513

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