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APPL1 Antibody

APPL1 Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenAPPL1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the APPL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis APPL1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9UKG1
PurityAntigen affinity
Description APPL1 is highly expressed in skeletal muscle, It contains 709 amino acids and shares a 54% amino acid identity with APPL2, It has been regarded as an adaptor that may tether inactive AKT2 to the PI3K in the cytoplasm and thereby may expedite recruitment of AKT2 and PI3K to the cell membrane upon mitogenic stimulation, and pancreas, heart, ovary, tissues in which AKT2 mRNA is abundant, DCC-interacting protein 13-alpha is a protein that in humans is encoded by the APPL1 gene
Immunogen mouse and rat), An amino acid sequence from the N-terminus of human APPL1 (NDHDAAINRYSRLSKKRENDK) was used as the immunogen for this APPL1 antibody (100% homologous in human
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the APPL1 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetAPPL1
Short nameAPPL1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameAPPL1 (Antibody to)
Alternative techniqueantibodies
Identity 24035
Gene APPL1
Long gene name adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
Synonyms gene name PH domain and leucine zipper containing 1 , adaptor protein, phosphotyrosine interaction
Synonyms APPL
Synonyms name DCC-interacting protein 13-alpha
Locus 3p14, 3
Discovery year 2007-01-26
GenBank acession AB037849
Entrez gene record 26060
Pubmed identfication 10490823 17030088
RefSeq identity NM_012096
Classification Pleckstrin homology domain containing BAR-PH domain containing
Havana BLAST/BLAT OTTHUMG00000133756

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