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APS(Ser597) Antibody, Biotin Conjugated

APS(Ser597) Antibody, Biotin Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name Biotin Conjugated, APS(Ser597) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAPS Ser597
SpecificityThis is a highly specific antibody against APS Ser597
ModificationPhosphorylation
Modification siteSer597
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from mouse APS around the phosphorylation site of Ser597
Gene ID number354
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Rat, Mouse
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A PH and an SH2 domain containing adaptor protein that links activated tyrosine kinases to signaling pathways, APS has been shown to inhibit the JAK STAT pathway in collaboration with cCbl, It is tyrosine phosphorylated by JAK2, KIT and other kinases during B cell receptor stimulation of many different cytokines, an adaptor protein that is involved in B cell signaling, chemokines and leukokines, insulin signaling and cytoskeletal reorganisation, APS (adapter protein with Pleckstrin homology and Src homology 2 domains) is a member of the Lnk family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms APS
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetAPS(Ser597) Conjugated
Short name Conjugated, APS(Ser597) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, APS(Ser597) (Antibody to)
Alternative techniqueantibodies
Identity 17381
Gene SH2B2
Long gene name SH2B adaptor protein 2
Synonyms name adaptor protein with pleckstrin homology and src
Locus 7q22, 1
Discovery year 2006-07-04
GenBank acession AB000520
Entrez gene record 10603
Pubmed identfication 9233773
RefSeq identity NM_020979
Classification Pleckstrin homology domain containing SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000150652

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