Name : APS(Ser597) Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN1823039449
| Long name | FITC Conjugated, APS(Ser597) Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | APS Ser597 |
| Specificity | This is a highly specific antibody against APS Ser597 |
| Modification | Phosphorylation |
| Modification site | Ser597 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from mouse APS around the phosphorylation site of Ser597 |
| Gene ID number | 354 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Rat, Mouse |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | A PH and an SH2 domain containing adaptor protein that links activated tyrosine kinases to signaling pathways, APS has been shown to inhibit the JAK STAT pathway in collaboration with cCbl, It is tyrosine phosphorylated by JAK2, KIT and other kinases during B cell receptor stimulation of many different cytokines, an adaptor protein that is involved in B cell signaling, chemokines and leukokines, insulin signaling and cytoskeletal reorganisation, APS (adapter protein with Pleckstrin homology and Src homology 2 domains) is a member of the Lnk family |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | APS |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | APS(Ser597) Conjugated |
| Short name | FITC Conjugated, APS(Ser597) Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, APS(Ser597) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 17381 |
| Gene | SH2B2 |
| Long gene name | SH2B adaptor protein 2 |
| Synonyms name | adaptor protein with pleckstrin homology and src |
| Locus | 7q22, 1 |
| Discovery year | 2006-07-04 |
| GenBank acession | AB000520 |
| Entrez gene record | 10603 |
| Pubmed identfication | 9233773 |
| RefSeq identity | NM_020979 |
| Classification | Pleckstrin homology domain containing SH2 domain containing |
| Havana BLAST/BLAT | OTTHUMG00000150652 |