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AQP3 Antibody / Aquaporin 3

AQP3 Antibody / Aquaporin 3 size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenAQP3 / Aquaporin 3
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ICC, IHC-F, IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Frozen): 0, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0
Notes Titration of the AQP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis AQP3 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q92482
PurityAntigen affinity
Description AQP3 appears to exist as a single copy and to comprise 6 exons distributed over 7 kb, By Western blot analysis and immunofluorescence microscopy of epidermis, It provides a short circuit for water, Sougrat et al, The gene is mapped to 9p21-p12 by fluorescence in situ hybridization, The protein is localized at the basal lateral membranes of collecting duct cells in the kidney, The protein works as water-channel and facilitates the transport of nonionic small solutes such as urea and glycerol, The results suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms, albeit to a smaller degree, between the base of the epidermis and the SC in order to maintain a constant H2O content and to prevent the formation of a continuous water gradient across the epidermis below the SC, one layer below the unstained stratum corneum(SC), or water-clamp, (2002) showed strong expression of an approximately 33-kD glycosylated AQP3 protein in keratinocyte plasma membranes, Aquaporin 3 is the third member of the major intrinsic protein family
ImmunogenAn amino acid sequence from the C-terminus of human Aquaporin 3 (EENVKLAHVKHKEQI) was used as the immunogen for this AQP3 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the AQP3 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetAQP3 / Aquaporin 3
Short nameAQP3 Antibody / Aquaporin 3
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameaquaporin 3 (Gill blood group) (Antibody to) / Aquaporin 3
Alternative techniqueantibodies
Alternative to gene target AQP-3 and GIL, AQP3 and IDBG-57960 and ENSG00000165272 and 360, AQP3 and IDBG-635798 and ENSBTAG00000008493 and 780866, Aqp3 and IDBG-137002 and ENSMUSG00000028435 and 11828, Cell surfaces, glycerol channel activity, this GO :0002684 and positive regulation of immune system process and biological process this GO :0005215 and transporter activity and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006810 and transport and biological process this GO :0006833 and water transport and biological process this GO :0007588 and excretion and biological process this GO :0015250 and water channel activity and molecular function this GO :0015254 and glycerol channel activity and molecular function this GO :0015793 and glycerol transport and biological process this GO :0015840 and urea transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016323 and basolateral plasma membrane and cellular component this GO :0032526 and response to retinoic acid and biological process this GO :0033280 and response to vitamin D and biological process this GO :0042476 and odontogenesis and biological process this GO :0045087 and innate immune response and biological process this GO :0045616 and regulation of keratinocyte differentiation and biological process this GO :0051592 and response to calcium ion and biological process this GO :0055085 and transmembrane transport and biological process this GO :0070295 and renal water absorption and biological process, this GO :0005215: transporter activity, this GO :0005215: transporter activity and also this GO :0015250: water channel activity and also this GO :0015254: glycerol channel activity, this GO :0015250: water channel activity, this GO :0015254: glycerol channel activity, aquaporin 3 (Gill blood group)
Identity 636
Gene AQP3
Long gene name aquaporin 3 (Gill blood group)
Synonyms gene name aquaporin 3 aquaporin 3 (GIL blood group)
Synonyms GIL
Synonyms name Gill blood group
Locus 9p13, 3
Discovery year 1994-07-25
Entrez gene record 360
Pubmed identfication 7558005
RefSeq identity NM_004925
Classification Aquaporins Blood group antigens
Havana BLAST/BLAT OTTHUMG00000019769
Locus Specific Databases LRG_821

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