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ARHGAP17 Antibody

ARHGAP17 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameARHGAP17 Primary Polyclonal Antibody
Also known asARHGAP17 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenARHGAP17
SpecificityThis is a highly specific antibody against ARHGAP17
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from fruit fly ARHGAP17/Nadrin
Gene ID number55114
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts as a GTPase activator in vitro for RAC1, It specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state, RHGAP17 participates in the Ca(2+)-dependent regulation of exocytosis, The complex formed with AMOT acts by regulating the uptake of polarity proteins at tight junctions, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments, possibly by deciding whether tight junction transmembrane proteins are recycled back to the plasma membrane or sent elsewhere, thereby playing a central role in apical polarity of epithelial cells, ARHGAP17 is a Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names MST066, MST110, MSTP038, NADRIN, Neuron associated developmentally regulated protein, PP367, PP4534, RICH 1, RICH1, RICH1B, Rho GTPase activating protein 17, Rho type GTPase activating protein 17, RhoGAP interacting with CIP4 homologs 1, RhoGAP interacting with CIP4 homologs protein 1, WBP15, ARHGAP17
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetARHGAP17
Short nameARHGAP17 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRho GTPase activating protein 17 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target ARHGAP17 and IDBG-21389 and ENSG00000140750 and 55114, ARHGAP17 and IDBG-638696 and ENSBTAG00000020043 and 504245, Arhgap17 and IDBG-209112 and ENSMUSG00000030766 and 70497, Cell surfaces, SH3 domain binding, this GO :0005096 and GTPase activator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005923 and tight junction and cellular component this GO :0007165 and signal transduction and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0016020 and membrane and cellular component this GO :0017124 and SH3 domain binding and molecular function this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process, this GO :0005096: GTPase activator activity, this GO :0005096: GTPase activator activity and also this GO :0005515: protein binding and also this GO :0017124: SH3 domain binding, this GO :0005515: protein binding, this GO :0017124: SH3 domain binding, Rho GTPase activating protein 17
Identity 18239
Gene ARHGAP17
Long gene name Rho GTPase activating protein 17
Synonyms RICH1 FLJ10308 NADRIN FLJ13219 WBP15
Locus 16p12, 1
Discovery year 2004-04-22
GenBank acession AJ306731
Entrez gene record 55114
Pubmed identfication 10967100 11431473
RefSeq identity NM_018054
Classification Rho GTPase activating proteins N-BAR domain containing
Havana BLAST/BLAT OTTHUMG00000177372

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