Name : ARHGAP24 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN1853076493
| Long name | ALEXA FLUOR 488 Conjugated, ARHGAP24 Polyclonal Antibody |
| Also known as | Anti-ARHGAP24 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | ARHGAP24 |
| Specificity | This is a highly specific antibody against ARHGAP24 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 630-680/748 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ARHGAP24 |
| Gene ID Number | 83478 |
| Swiss Prot | Q8N264 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Able to suppress RAC1 and CDC42 activity in vitro, Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state, Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity, Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis, Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, and filopodia, cell morphology and cytoskeletal organization, lamellipodia, Rho GTPase-activating protein involved in cell polarity |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | DKFZP564B1162 FLJ33877 FilGAP |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the ARHGAP24 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | ARHGAP24 |
| Short name | ARHGAP24 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, ARHGAP24 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 25361 |
| Gene | ARHGAP24 |
| Long gene name | Rho GTPase activating protein 24 |
| Locus | 4q21, 23-q21, 3 |
| Discovery year | 2004-04-06 |
| GenBank acession | AK091196 |
| Entrez gene record | 83478 |
| Pubmed identfication | 11230166 15254788 |
| RefSeq identity | NM_031305 |
| Classification | Pleckstrin homology domain containing Rho GTPase activating proteins |
| Havana BLAST/BLAT | OTTHUMG00000130427 |