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ARHGAP24 Antibody, Biotin Conjugated

ARHGAP24 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, ARHGAP24 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenARHGAP24
SpecificityThis is a highly specific antibody against ARHGAP24
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range630-680/748
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human ARHGAP24
Gene ID number83478
Swiss ProtQ8N264
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Able to suppress RAC1 and CDC42 activity in vitro, Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state, Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity, Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis, Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, and filopodia, cell morphology and cytoskeletal organization, lamellipodia, Rho GTPase-activating protein involved in cell polarity
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms DKFZP564B1162 FLJ33877 FilGAP
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetARHGAP24 Conjugated
Short name Conjugated, ARHGAP24 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, ARHGAP24 (Antibody to)
Alternative techniqueantibodies
Identity 25361
Gene ARHGAP24
Long gene name Rho GTPase activating protein 24
Locus 4q21, 23-q21, 3
Discovery year 2004-04-06
GenBank acession AK091196
Entrez gene record 83478
Pubmed identfication 11230166 15254788
RefSeq identity NM_031305
Classification Pleckstrin homology domain containing Rho GTPase activating proteins
Havana BLAST/BLAT OTTHUMG00000130427

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