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ARID1B Antibody

ARID1B Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameARID1B Primary Polyclonal Antibody
Also known asARID1B PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenARID1B
SpecificityThis is a highly specific antibody against ARID1B
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range1550-1600/2236
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ARID1B
Gene ID number57492
Swiss ProtQ8NFD5
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen As neural progenitors exit mitosis and differentiate into neurons, Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex), Binds DNA non-specifically, During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state, The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity), The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells, The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF), npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 6A3-5, ARID domain-containing protein 1B, ARID1B, AT-rich interactive domain-containing protein 1B, BAF250B, BRG1-associated factor 250b, BRG1-binding protein hELD/OSA1, BRIGHT, DAN15, ELD/OSA1, KIAA1235, MRD12, Osa homolog 2, P250R, hOsa2, OSA2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetARID1B
Short nameARID1B Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameARID1B (Antibody to)
Alternative techniqueantibodies
Identity 18040
Gene ARID1B
Long gene name AT-rich interaction domain 1B
Synonyms gene name AT rich interactive domain 1B (SWI1-like)
Synonyms KIAA1235 ELD/OSA1 p250R BAF250b DAN15 6A3-5
Locus 6q25, 3
Discovery year 2004-01-28
GenBank acession AF521671
Entrez gene record 57492
RefSeq identity NM_020732
Classification AT-rich interaction domain containing
Havana BLAST/BLAT OTTHUMG00000015890
Locus Specific Databases LRG_861

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