Name : ARID1B Antibody, ALEXA FLUOR 350
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN5820490300
| Long name | ALEXA FLUOR 350 Conjugated, ARID1B Polyclonal Antibody |
| Also known as | Anti-ARID1B PAb ALEXA FLUOR 350 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 350, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | ARID1B |
| Specificity | This is a highly specific antibody against ARID1B |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 1550-1600/2236 |
| Subcellular location | Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ARID1B |
| Gene ID Number | 57492 |
| Swiss Prot | Q8NFD5 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | As neural progenitors exit mitosis and differentiate into neurons, Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex), Binds DNA non-specifically, During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state, The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity), The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells, The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF), npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology) |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 343nm/442nm |
| Synonyms | KIAA1235 ELD/OSA1 p250R BAF250b DAN15 6A3-5 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 350, Alexa Fluor |
| Gene target | ARID1B |
| Short name | ARID1B Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 350 |
| Alternative name | ALEXA FLUOR 350, ARID1B (Antibody to) |
| Alternative technique | antibodies |
| Identity | 18040 |
| Gene | ARID1B |
| Long gene name | AT-rich interaction domain 1B |
| Synonyms gene name | AT rich interactive domain 1B (SWI1-like) |
| Locus | 6q25, 3 |
| Discovery year | 2004-01-28 |
| GenBank acession | AF521671 |
| Entrez gene record | 57492 |
| RefSeq identity | NM_020732 |
| Classification | AT-rich interaction domain containing |
| Havana BLAST/BLAT | OTTHUMG00000015890 |
| Locus Specific Databases | LRG_861 |