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Aromatase Antibody (CYP19A1)

Aromatase Antibody (CYP19A1) size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenAromatase (CYP19A1)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the Aromatase antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis Aromatase antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P11511
PurityPurified
Description Mutations in this gene can result in either increased or decreased aromatase activity, The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids, the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation, three successive hydroxylations of the A ring of androgens, CYP19A1/Aromatase is a member of the cytochrome P450 superfamily of enzymes, This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis
ImmunogenA portion of amino acids 221-253 from the human protein was used as the immunogen for this Aromatase antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Aromatase antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetAromatase (CYP19A1)
Short nameAromatase Antibody (CYP19A1)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameAromatase (Antibody to) (CYP19A1)
Alternative techniqueantibodies
Identity 2594
Gene CYP19A1
Long gene name cytochrome P450 family 19 subfamily A member 1
Synonyms gene CYP19
Synonyms gene name cytochrome P450, family 19, polypeptide 1 , subfamily A, subfamily XIX (aromatization of androgens) cytochrome P450
Synonyms ARO P-450AROM CPV1 ARO1 CYAR aromatase
Locus 15q21, 2
Discovery year 1986-01-01
GenBank acession D14473
Entrez gene record 1588
Pubmed identfication 8477708
Classification Cytochrome P450 family 19
Havana BLAST/BLAT OTTHUMG00000131747
Locus Specific Databases Human Cytochrome P450 (CYP) Allele Nomenclature Committee

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