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ARP2/ARP3 Antibody

ARP2/ARP3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameARP2/ARP3 Primary Polyclonal Antibody
Also known asARP2/ARP3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenARP2/ARP3
SpecificityThis is a highly specific antibody against ARP2/ARP3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ARP2/ARP3
Gene ID number10097
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Cells trigger actin polymerization through either the de novo nucleation of filaments from monomeric actin, In addition, In response to GTP-binding Cdc42, The Arp2/3 complex consists of the actin-related proteins Arp2 and Arp3, The Arp2/3 complex promotes actin nucleation by binding the pointed end of actin filaments, The nucleation of actin is a rate-limiting and unfavorable reaction in actin polymerization and therefore requires the involvement of the Arp2/3 complex, and initiates the formation of lamellipodia and filopodia, and nucleates growth in the barbed direction, and platelet activation, and various other accessory proteins, cell adhesion, cell migration, including chemotaxis, namely the WASP proteins, or by associating with the side of an existing filament, or the uncapping of existing barbed ends, the Arp2/3 complex also mediates actin cytoskeletal outgrowths that are regulated by the Rho family of small GTPases, the Arp2/3 complex binds the Cdc42 substrates, the severing of existing filaments to create uncapped barbed ends, which helps create new filaments and promotes the end-to-side cross-linking of actin filaments into the branching meshwork, Actin polymerization is required for a variety of cell functions
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ACTIN-RELATED PROTEIN 2, ACTR2, ARP2, ARP2 actin related protein 2 homolog yeast, ARP2/3 COMPLEX, ARP2_HUMAN, Actin related protein 2, Actin-like protein 2, OTTHUMP00000159937, OTTHUMP00000202270, Actin like protein 2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetARP2/ARP3
Short nameARP2/ARP3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameARP2/ARP3 (Antibody to)
Alternative techniqueantibodies
Identity 169
Gene ACTR2
Long gene name ARP2 actin related protein 2 homolog
Synonyms gene name ARP2 (actin-related protein 2, yeast) homolog ARP2 actin-related protein 2 homolog (yeast)
Synonyms ARP2
Locus 2p14
Discovery year 1999-05-17
GenBank acession AF006082
Entrez gene record 10097
Pubmed identfication 9230079
RefSeq identity NM_001005386
Classification Actin related protein 2/3 complex
Havana BLAST/BLAT OTTHUMG00000129540

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