ASAH1 Antibody, Biotin Conjugated

ASAH1 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	Biotin Conjugated, ASAH1 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	ASAH1
Specificity	This is a highly specific antibody against ASAH1
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Source	KLH conjugated synthetic peptide derived from human Acid ceramidase subunit beta
Gene ID number	427
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	Bioinformatic analysis of gene expression also reveals acid ceramidase to be among the 5 most important genes associated with melanoma, Effected individuals experience early onset joint problems and neurological problems, In addition to ceramide hydrolysis, Interestingly, a hallmark of Farber disease, and deficiency leads to accumulation of ceramide in tissues, for hydrolysis the pH optimum is 4, further supporting a complex and central role for acid ceramidase in sphingolipid metabolism, owing to mutations in the acid ceramidase gene, pH regulates which reaction is favored, purified acid ceramidase also exhibits the ability to catalyze ceramide synthesis, utilizing [14C]lauric acid and sphingosine as substrates, whereas for the reverse reaction favors a pH of 5, 5, 5, Acid ceramidase catalyzes the degradation of ceramide in normal tissues
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Synonyms	AC PHP32 FLJ21558 ACDase
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	ASAH1 Conjugated
Short name	Conjugated, ASAH1 Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, ASAH1 (Antibody to)
Alternative technique	antibodies
Identity	735
Gene	ASAH1
Long gene name	N-acylsphingosine amidohydrolase 1
Synonyms gene	ASAH
Synonyms gene name	N-acylsphingosine amidohydrolase (acid ceramidase)
Synonyms name	acylsphingosine deacylase acid ceramidase
Locus	8p22
Discovery year	1997-08-22
GenBank acession	U70063
Entrez gene record	427
Pubmed identfication	8955159 10610716
RefSeq identity	NM_004315
Havana BLAST/BLAT	OTTHUMG00000096997

ASAH1 Antibody, Biotin Conjugated

ASAH1 Antibody, Biotin Conjugated size: 0.1ml 333

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