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ASAH2 Antibody

ASAH2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameASAH2 Primary Polyclonal Antibody
Also known asASAH2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenASAH2
SpecificityThis is a highly specific antibody against ASAH2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ASAH2
Gene ID number2298
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface, Acts as a repressor of apoptosis both by reducing C16-ceramide, Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract, a precursor of the antiapoptotic factor sphingosine 1-phosphate, and generating sphingosine, thereby preventing ceramide-induced apoptosis, 5, 5-8, Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ASAH2, ASAH2_HUMAN, BCDase, HNAC1, LCDase, MGC129777, N CDase, N acylsphingosine amidohydrolase 2, N acylsphingosine amidohydrolase non lysosomal ceramidase 2, N-CDase, N-acylsphingosine amidohydrolase 2, NCDase, Neutral ceramidase soluble form, Non lysosomal ceramidase, Non-lysosomal ceramidase, hCD, mitochondrial ceramidase, Acylsphingosine deacylase 2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetASAH2
Short nameASAH2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameN-acylsphin this GO sine amidohydrolase (non-lysosomal ceramidase) 2 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target ASAH2 and IDBG-74349 and ENSG00000188611 and 56624, Plasma membranes, ceramidase activity, this GO :0005739 and mitochondrion and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006665 and sphin this GO lipid metabolic process and biological process this GO :0006672 and ceramide metabolic process and biological process this GO :0006687 and glycosphin this GO lipid metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0017040 and ceramidase activity and molecular function this GO :0044281 and small molecule metabolic process and biological process, this GO :0017040: ceramidase activity, this GO :0017040: ceramidase activity, N-acylsphin this GO sine amidohydrolase (non-lysosomal ceramidase) 2
Identity 18860
Gene ASAH2
Long gene name N-acylsphingosine amidohydrolase 2
Synonyms gene name N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
Synonyms name neutral ceramidase non-lysosomal ceramidase
Locus 10q11, 23
Discovery year 2002-07-05
GenBank acession AF250847
Entrez gene record 56624
Pubmed identfication 10781606
RefSeq identity NM_019893
Havana BLAST/BLAT OTTHUMG00000018223

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