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ASB3 Antibody

ASB3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameASB3 Primary Polyclonal Antibody
Also known asASB3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenASB3
SpecificityThis is a highly specific antibody against ASB3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ASB3
Gene ID number51130
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen ASB-1 is expressed in multiple organs, ASB-1 knock-out mice display a diminution of spermatogenesis with less complete filling of seminiferous tubules, ASB-2, ASB-2 is directly induced by all-trans retinotic acid, ASB-3 and ASB-4, Asb-2 is a novel retinoic-acid (RA)-induced gene in acute promyelocytic leukemia (APL) cells and its expression induces growth-inhibition and chromatin condensation recapitulating early events critical to RA-induced differentiaiton of APL cells, Four members of the ankyrin repeat and SOCS box-containing (ASB) protein family are identified and termed as ASB-1, Serveral other families of proteins also contain SOCS boxes but differ from the SOCS proteins in the type of domain they contained upstream of the SOCS box, by the binding of RARa to the RAR binding element/RXR binding element in the Asb-2 promoter, including the hematopoietic compartment, which serves to couple SOCS proteins and their binding partners with the elongin B and C complex, Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ASB-3, ASB3, ASB3_HUMAN, Ankyrin repeat and SOCS box containing protein 3, Ankyrin repeat and SOCS box protein 3, Weakly similar to ankyrin brain variant 2, Ankyrin repeat and SOCS box containing 3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetASB3
Short nameASB3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameASB3 (Antibody to)
Alternative techniqueantibodies
Identity 16013
Gene ASB3
Long gene name ankyrin repeat and SOCS box containing 3
Synonyms gene name ankyrin repeat and SOCS box-containing 3
Synonyms ASB-3
Locus 2p16, 2
Discovery year 2001-06-29
GenBank acession AK000985
Entrez gene record 51130
Pubmed identfication 15899873
RefSeq identity NM_016115
Classification Ankyrin repeat domain containing
Havana BLAST/BLAT OTTHUMG00000184778

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