Name : ASB3 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN1950623339
| Long name | Biotin Conjugated, ASB3 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | ASB3 |
| Specificity | This is a highly specific antibody against ASB3 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human ASB3 |
| Gene ID number | 51130 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | ASB-1 is expressed in multiple organs, ASB-1 knock-out mice display a diminution of spermatogenesis with less complete filling of seminiferous tubules, ASB-2, ASB-2 is directly induced by all-trans retinotic acid, ASB-3 and ASB-4, Asb-2 is a novel retinoic-acid (RA)-induced gene in acute promyelocytic leukemia (APL) cells and its expression induces growth-inhibition and chromatin condensation recapitulating early events critical to RA-induced differentiaiton of APL cells, Four members of the ankyrin repeat and SOCS box-containing (ASB) protein family are identified and termed as ASB-1, Serveral other families of proteins also contain SOCS boxes but differ from the SOCS proteins in the type of domain they contained upstream of the SOCS box, by the binding of RARa to the RAR binding element/RXR binding element in the Asb-2 promoter, including the hematopoietic compartment, which serves to couple SOCS proteins and their binding partners with the elongin B and C complex, Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | ASB-3 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ASB3 Conjugated |
| Short name | Conjugated, ASB3 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, ASB3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 16013 |
| Gene | ASB3 |
| Long gene name | ankyrin repeat and SOCS box containing 3 |
| Synonyms gene name | ankyrin repeat and SOCS box-containing 3 |
| Locus | 2p16, 2 |
| Discovery year | 2001-06-29 |
| GenBank acession | AK000985 |
| Entrez gene record | 51130 |
| Pubmed identfication | 15899873 |
| RefSeq identity | NM_016115 |
| Classification | Ankyrin repeat domain containing |
| Havana BLAST/BLAT | OTTHUMG00000184778 |