| Alternative name1 | ASK-1, MAP3K5, MAPK/ERK Kinase Kinase 5, MAPKKK5, MEK Kinase 5, MEKK 5, MEKK5), Mitogen-activated Protein Kinase Kinase Kinase 5, phosphorylated (Ser83) (Apoptosis Signal-regulating Kinase 1, Anti-ASK1 |
| Alternative name2 | ASK-1, MAP3K5, MAPK/ERK Kinase Kinase 5, MAPKKK5, MEK Kinase 5, MEKK 5, MEKK5), Mitogen-activated Protein Kinase Kinase Kinase 5, phosphorylated (Ser83) (Apoptosis Signal-regulating Kinase 1, ASK1 |
| Alternative name3 | ASK-1, MAP3K5, MAPK/ERK Kinase Kinase 5, MAPKKK5, MEK Kinase 5, MEKK 5, MEKK5), Mitogen-activated Protein Kinase Kinase Kinase 5, phosphorylated (Ser83) (Apoptosis Signal-regulating Kinase 1, ASK1 |
| Alternative name4 | ASK1 |
| Alternative name5 | ASK-1, MAP3K5, MAPK/ERK Kinase Kinase 5, MAPKKK5, MEK Kinase 5, MEKK 5, MEKK5), Mitogen-activated Protein Kinase Kinase Kinase 5, phosphorylated (Ser83) (Apoptosis Signal-regulating Kinase 1, Anti -ASK1 |
| Other names | N/A, ASK1 |
| Gene name | N/A |
| Gene name synonims | N/A |
| Other gene names | N/A |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | IgG |
| Clone | Polyclonal antibody |
| Host organism | Source: Human, Host: Rabbit |
| Species reactivity | Human |
| Specificity and cross-reactivity | Detects overexpressed human ASK1 only when phosphorylated at Ser83 |
| Purification method | Affinity Purified by protein A and immunoaffinity chromatography |
| Form/Appearance | 0, 150mM sodium chloride, 50% glycerol, pH 7, 1mg/ml BSA, 5, Supplied as a liquid in 10mM sodium HEPES |
| Concentration | N/A |
| Storage and shipping | Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage, For maximum recovery of product, For optimal long term storage, Further dilutions can be made in assay buffer, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for: | Immunoprecipitation (IP), Western Blot (WB) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target | ASK-1, MAP3K5, MAPK/ERK Kinase Kinase 5, MAPKKK5, MEK Kinase 5, MEKK 5, MEKK5), Mitogen-activated Protein Kinase Kinase Kinase 5, phosphorylated (Ser83) Signal-regulating Kinase 1, ASK1 |
| Short name | ASK-1, MAP3K5, MAPK/ERK Kinase Kinase 5, MAPKKK5, MEK Kinase 5, MEKK 5, MEKK5) Antibody, Mitogen-activated Protein Kinase Kinase Kinase 5, phosphorylated (Ser83) (Apoptosis Signal-regulating Kinase 1, ASK1 |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | ASK-1, MAPK/ERK phosphorylation catalyst Kinase 5, MAPKKK5, MEK phosphorylation catalyst 5, MEKK 5, MEKK5) (Antibody to), Mitogen-activated Protein phosphorylation catalyst Kinase phosphorylation catalyst 5, mitogen-activated protein phosphorylation catalyst kinase phosphorylation catalyst 5, phosphorylated (Ser83) (programmed cellular destruction Signal-regulating phosphorylation catalyst 1, ASK1 |
| Alternative technique | antibodies |
| Alternative to gene target | ASK1 and MAPKKK5 and MEKK5, BT, Cytoplasm, MAP3K5 and IDBG-96934 and ENSG00000197442 and 4217, Map3k5 and IDBG-136255 and ENSMUSG00000071369 and 26408, this GO :0000165 and MAPK cascade and biological process this GO :0000186 and activation of MAPKK activity and biological process this GO :0000187 and activation of MAPK activity and biological process this GO :0000287 and magnesium ion binding and molecular function this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002931 and response to ischemia and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004709 and MAP kinase kinase kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007254 and JNK cascade and biological process this GO :0007257 and activation of JUN kinase activity and biological process this GO :0008631 and intrinsic apoptotic signaling pathway in response to oxidative stress and biological process this GO :0008656 and cysteine-type endopeptidase activator activity involved in apoptotic process and molecular function this GO :0010941 and regulation of cell death and biological process this GO :0016032 and viral process and biological process this GO :0016772 and transferase activity, this GO :0000287: magnesium ion binding, this GO :0000287: magnesium ion binding and also this GO :0004672: protein kinase activity and also this GO :0004709: MAP kinase kinase kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0008656: cysteine-type endopeptidase activator activity involved in apoptotic process and also this GO :0016772: transferase activity, this GO :0004672: protein kinase activity, this GO :0004709: MAP kinase kinase kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0008656: cysteine-type endopeptidase activator activity involved in apoptotic process, this GO :0016772: transferase activity, this GO :0019901: protein kinase binding, this GO :0019903: protein phosphatase binding, this GO :0042803: protein homodimerization activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019901: protein kinase binding and also this GO :0019903: protein phosphatase binding and also this GO :0042803: protein homodimerization activity, transferring phosphorus-containing groups and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0019903 and protein phosphatase binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0070301 and cellular response to hydrogen peroxide and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097300 and programmed necrotic cell death and biological process this GO :1901216 and positive regulation of neuron death and biological process this GO :1902170 and cellular response to reactive nitrogen species and biological process this GO :1902911 and protein kinase complex and cellular component, 31917 and IDBG-633632 and ENSBTAG00000009065 and 100851608, 537380, mitogen-activated protein kinase kinase kinase 5 |
| Identity | 6857 |
| Gene | MAP3K5 |
| Long gene name | mitogen-activated protein kinase kinase kinase 5 |
| Synonyms gene | MEKK5 |
| Synonyms | MAPKKK5 ASK1 |
| Synonyms name | apoptosis signal regulating kinase 1 |
| Locus | 6q23, 3 |
| Discovery year | 1997-11-14 |
| GenBank acession | U67156 |
| Entrez gene record | 4217 |
| Pubmed identfication | 9465908 |
| Classification | Mitogen-activated protein kinase kinase kinases |
| Havana BLAST/BLAT | OTTHUMG00000015647 |
| Locus Specific Databases | The Globin Gene Server |
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