Name : ASK1 (Ser83) Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN4517549511
| Long name | ASK1 (Ser83) Primary Polyclonal Antibody |
| Also known as | ASK1 (Ser83) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | ASK1 Ser83 |
| Specificity | This is a highly specific antibody against ASK1 Ser83 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Ser83 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human ASK1 around the phosphorylation site of Ser83 |
| Gene ID number | 4217 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Drosophila, MAPK kinase (MKK or MEK), MAPK kinase/MEK, MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPKK4) in vitro, MAPKKK5 contains 1, MAPKKK5 does not activate MAPK/ERK, Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas, The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, The kinases of these signaling cascades are highly conserved, and MAPK kinase kinase (MAPKKK or MEKK), and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells, and homologs exist in yeast, and mammalian cells, which in turn activates MAPK, 374 amino acids with all 11 kinase subdomains, Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ASK-1, ASK1, ASK1Ser83, Apoptosis signal-regulating kinase 1, M3K5_HUMAN, MAP3K5, MAP3K5phospho S83, MAPK/ERK kinase kinase 5, MAPKKK5, MEK kinase 5, MEKK 5, MEKK5, Mitogen-activated protein kinase kinase kinase 5, p-ASK1 phospho S83, ASK1 phospho S83 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ASK1 (Ser83) |
| Short name | ASK1 (Ser83) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | ASK1 (Ser83) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 6857 |
| Gene | MAP3K5 |
| Long gene name | mitogen-activated protein kinase kinase kinase 5 |
| Synonyms gene | MEKK5 |
| Synonyms | MAPKKK5 ASK1 |
| Synonyms name | apoptosis signal regulating kinase 1 |
| Locus | 6q23, 3 |
| Discovery year | 1997-11-14 |
| GenBank acession | U67156 |
| Entrez gene record | 4217 |
| Pubmed identfication | 9465908 |
| Classification | Mitogen-activated protein kinase kinase kinases |
| Havana BLAST/BLAT | OTTHUMG00000015647 |
| Locus Specific Databases | The Globin Gene Server |