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ASL/Argininosuccinate Lyase Antibody, Biotin Conjugated

ASL/Argininosuccinate Lyase Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, ASL/Argininosuccinate Lyase Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenASL/Argininosuccinate Lyase
SpecificityThis is a highly specific antibody against ASL/Argininosuccinate Lyase
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human ASL/Argininosuccinate Lyase
Gene ID number435
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background ASL catalyzes the hydrolytic cleavage of argininosuccinic acid (ASA) to fumarate and arginine, ASL shares high sequence homology with the avian and reptilian eye lens protein, In addition, Localizing to the cytoplasm and existing as a homotetramer, Mutations in the gene encoding ASL leads to an accumulation of ASA in body fluids and results in Arginosuc-cinic aciduria (ASAuria), This reaction is also involved in the biosynthesis of arginine, an autosomal recessive disorder that is characterized by hyperammonemia, an essential step of the urea cycle which is crucial for the detoxification of ammonia, convulsions, d-crystallin, episodic unconsciousness and dry and brittle hair showing trich-orrhexis nodosa (weak points or nodes in the hair shaft), liver enlargement, physical and mental retardation, ASL is a member of the lyase 1 family of proteins and is predominantly expressed in the liver
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetASL/Argininosuccinate Lyase Conjugated
Short name Conjugated, ASL/Argininosuccinate Lyase Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, ASL/Argininosuccinate Lyase (Antibody to)
Alternative techniqueantibodies
Identity 746
Gene ASL
Long gene name argininosuccinate lyase
Locus 7q11, 21
Discovery year 2001-06-22
Entrez gene record 435
RefSeq identity NM_000048
Havana BLAST/BLAT OTTHUMG00000022876
Locus Specific Databases LOVD - Leiden Open Variation Database

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