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Ataxin 7 Antibody

Ataxin 7 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameAtaxin 7 Primary Polyclonal Antibody
Also known asAtaxin 7 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenAtaxin 7
SpecificityThis is a highly specific antibody against Ataxin 7
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ataxin 7
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Ataxin-7 is expressed within neurons both affected and unaffected in SCA7 pathology with subcellular localization being variable depending upon the neuronal subtype (5), Polyglutamine expanded in ataxin-7 may carry out its pathogenic effects in the nucleus by altering the matrix-associated nuclear structure and/or by disrupting nucleolar function (6), SCA7 is an autosomal dominant neurodegenerative disorder characterized by ataxia and selective neuronal cell loss caused by the expansion of a translated CAG repeat encoding a polyglutamine tract in ataxin-7, also known as spinocerebellar ataxia 7 or SCA7, and encodes a 892 amino acid protein containing a nuclear localization signal and a polyglutamine tract (1, has a 2, maps to chromosome 3p13-p12, which is the SCA7 gene product (3, 2), 4), 727-bp open reading frame, The human ataxin-7 gene
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ADCAII, ATX7_HUMAN, ATXN 7, Ataxin-7, OPCA III, OPCA3, SCA 7, SCA7, Spinocerebellar Ataxia 7, Spinocerebellar ataxia type 7 protein, Ataxin7
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetAtaxin 7
Short nameAtaxin 7 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameAtaxin 7 (Antibody to)
Alternative techniqueantibodies
Identity 28481
Gene ATXN7L4
Long gene name ataxin 7 like 1
Synonyms gene name ataxin 7-like 4 ataxin 7-like 1
Synonyms KIAA1218 MGC33190 ATXN7L1
Locus 7q22, 3
Discovery year 2004-08-18
GenBank acession AB033044
Entrez gene record 222255
Pubmed identfication 15115762
Havana BLAST/BLAT OTTHUMG00000157521

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