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Ataxin 7 Antibody, ALEXA FLUOR 594

Ataxin 7 Antibody, ALEXA FLUOR 594 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 594 Conjugated, Ataxin 7 Polyclonal Antibody
Also known asAnti-Ataxin 7 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenAtaxin 7
SpecificityThis is a highly specific antibody against Ataxin 7
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ataxin 7
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Ataxin-7 is expressed within neurons both affected and unaffected in SCA7 pathology with subcellular localization being variable depending upon the neuronal subtype (5), Polyglutamine expanded in ataxin-7 may carry out its pathogenic effects in the nucleus by altering the matrix-associated nuclear structure and/or by disrupting nucleolar function (6), SCA7 is an autosomal dominant neurodegenerative disorder characterized by ataxia and selective neuronal cell loss caused by the expansion of a translated CAG repeat encoding a polyglutamine tract in ataxin-7, also known as spinocerebellar ataxia 7 or SCA7, and encodes a 892 amino acid protein containing a nuclear localization signal and a polyglutamine tract (1, has a 2, maps to chromosome 3p13-p12, which is the SCA7 gene product (3, 2), 4), 727-bp open reading frame, The human ataxin-7 gene
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms KIAA1218 MGC33190 ATXN7L1
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetAtaxin 7
Short nameAtaxin 7 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, Ataxin 7 (Antibody to)
Alternative techniqueantibodies
Identity 28481
Gene ATXN7L4
Long gene name ataxin 7 like 1
Synonyms gene name ataxin 7-like 4 ataxin 7-like 1
Locus 7q22, 3
Discovery year 2004-08-18
GenBank acession AB033044
Entrez gene record 222255
Pubmed identfication 15115762
Havana BLAST/BLAT OTTHUMG00000157521

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