Name : Ataxin 7 Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN4958081983
| Long name | ALEXA FLUOR 594 Conjugated, Ataxin 7 Polyclonal Antibody |
| Also known as | Anti-Ataxin 7 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Ataxin 7 |
| Specificity | This is a highly specific antibody against Ataxin 7 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ataxin 7 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Ataxin-7 is expressed within neurons both affected and unaffected in SCA7 pathology with subcellular localization being variable depending upon the neuronal subtype (5), Polyglutamine expanded in ataxin-7 may carry out its pathogenic effects in the nucleus by altering the matrix-associated nuclear structure and/or by disrupting nucleolar function (6), SCA7 is an autosomal dominant neurodegenerative disorder characterized by ataxia and selective neuronal cell loss caused by the expansion of a translated CAG repeat encoding a polyglutamine tract in ataxin-7, also known as spinocerebellar ataxia 7 or SCA7, and encodes a 892 amino acid protein containing a nuclear localization signal and a polyglutamine tract (1, has a 2, maps to chromosome 3p13-p12, which is the SCA7 gene product (3, 2), 4), 727-bp open reading frame, The human ataxin-7 gene |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | KIAA1218 MGC33190 ATXN7L1 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | Ataxin 7 |
| Short name | Ataxin 7 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, Ataxin 7 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 28481 |
| Gene | ATXN7L4 |
| Long gene name | ataxin 7 like 1 |
| Synonyms gene name | ataxin 7-like 4 ataxin 7-like 1 |
| Locus | 7q22, 3 |
| Discovery year | 2004-08-18 |
| GenBank acession | AB033044 |
| Entrez gene record | 222255 |
| Pubmed identfication | 15115762 |
| Havana BLAST/BLAT | OTTHUMG00000157521 |