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ATF2 Antibody, ALEXA FLUOR 647

ATF2 Antibody, ALEXA FLUOR 647 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 647 Conjugated, ATF2 Polyclonal Antibody
Also known asAnti-ATF2 PAb ALEXA FLUOR 647
CategoryConjugated Primary Antibodies
Conjugated with 647, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenATF2
SpecificityThis is a highly specific antibody against ATF2
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range415-455/505
Subcellular location Mitochondrion, Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ATF2
Gene ID Number1386
Swiss ProtP15336
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Can elicit oncogenic or tumor suppressor activities depending on the tissue or cell type, Dependent on its binding partner, Exhibits histone acetyltransferase (HAT) activity which specifically acetylates histones H2B and H4 in vitro, In concert with CUL3 and RBX1, In the cytoplasm, In the nucleus, The phosphorylated form (mediated by ATM) plays a role in the DNA damage response and is involved in the ionizing radiation (IR)-induced S phase checkpoint control and in the recruitment of the MRN complex into the IR-induced foci (IRIF), and DNA damage response, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA-3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA-3'), cell growth, contributes to global transcription and the DNA damage response, in addition to specific transcriptional activities that are related to cell development, including those involved in anti-apoptosis, inducing mitochondrial leakage and promoting cell death, interacts with and perturbs HK1- and VDAC1-containing complexes at the mitochondrial outer membrane, proliferation and death, promotes the degradation of KAT5 thereby attenuating its ability to acetylate and activate ATM, thereby impairing mitochondrial membrane potential, Transcriptional activator which regulates the transcription of various genes
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission650nm/665nm
Synonyms ATF1 ATF2 HFB1-GDNF
Properties ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the ATF2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 647, Alexa Fluor
Gene targetATF2
Short nameATF2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 647
Alternative name ALEXA FLUOR 647, ATF2 (Antibody to)
Alternative techniqueantibodies
Identity 4232
Gene GDNF
Long gene name glial cell derived neurotrophic factor
Synonyms name astrocyte-derived trophic factor glial cell line derived neurotrophic factor glial derived neurotrophic factor
Locus 5p13, 2
Discovery year 1995-05-04
Entrez gene record 2668
Pubmed identfication 8493557
RefSeq identity NM_000514
Classification Endogenous ligands
Havana BLAST/BLAT OTTHUMG00000090809

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