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ATF4/CREB-2 Antibody, ALEXA FLUOR 488

ATF4/CREB-2 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, ATF4/CREB-2 Polyclonal Antibody
Also known asAnti-ATF4/CREB-2 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenATF4/CREB-2
SpecificityThis is a highly specific antibody against ATF4/CREB-2
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range240-290/351
Subcellular location Cell membrane, Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ATF4
Gene ID Number468
Swiss ProtP18848
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Activates transcription of SIRT4, Binds in a circadian time-dependent manner to the cAMP response elements (CRE) in the SLC6A4 and PER2 promoters and periodically activates the transcription of these genes, Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production (By similarity), In concert with DDIT3/CHOP, It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I, Regulates the circadian expression of the core clock component PER2 and the serotonin transporter SLC6A4, Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to ER stress, a sequence present in many viral and cellular promoters, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis by regulating the transcriptional induction of BBC3/PUMA, Transcriptional activator
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms TAXREB67 CREB-2
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the ATF4/CREB-2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetATF4/CREB-2
Short nameATF4/CREB-2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, ATF4/CREB-2 (Antibody to)
Alternative techniqueantibodies
Identity 786
Gene ATF4
Long gene name activating transcription factor 4
Synonyms gene TXREB
Synonyms gene name activating transcription factor 4 (tax-responsive enhancer element B67)
Synonyms name tax-responsive enhancer element B67
Locus 22q13, 1
Discovery year 1992-06-09
GenBank acession D90209
Entrez gene record 468
Pubmed identfication 1847461 1534408
RefSeq identity NM_001675
Classification Basic leucine zipper proteins
Havana BLAST/BLAT OTTHUMG00000151099

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