ATF4/CREB-2 Antibody, Biotin Conjugated

ATF4/CREB-2 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	Biotin Conjugated, ATF4/CREB-2 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	ATF4/CREB-2
Specificity	This is a highly specific antibody against ATF4/CREB-2
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Immunogen_range	240-290/351
Subcellular location	Cell membrane, Nucleus, Cytoplasm
Source	KLH conjugated synthetic peptide derived from human ATF4
Gene ID number	468
Swiss Prot	P18848
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	Activates transcription of SIRT4, Binds in a circadian time-dependent manner to the cAMP response elements (CRE) in the SLC6A4 and PER2 promoters and periodically activates the transcription of these genes, Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production (By similarity), In concert with DDIT3/CHOP, It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I, Regulates the circadian expression of the core clock component PER2 and the serotonin transporter SLC6A4, Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to ER stress, a sequence present in many viral and cellular promoters, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis by regulating the transcriptional induction of BBC3/PUMA, Transcriptional activator
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Synonyms	TAXREB67 CREB-2
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	ATF4/CREB-2 Conjugated
Short name	Conjugated, ATF4/CREB-2 Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, ATF4/CREB-2 (Antibody to)
Alternative technique	antibodies
Identity	786
Gene	ATF4
Long gene name	activating transcription factor 4
Synonyms gene	TXREB
Synonyms gene name	activating transcription factor 4 (tax-responsive enhancer element B67)
Synonyms name	tax-responsive enhancer element B67
Locus	22q13, 1
Discovery year	1992-06-09
GenBank acession	D90209
Entrez gene record	468
Pubmed identfication	1847461 1534408
RefSeq identity	NM_001675
Classification	Basic leucine zipper proteins
Havana BLAST/BLAT	OTTHUMG00000151099

ATF4/CREB-2 Antibody, Biotin Conjugated

ATF4/CREB-2 Antibody, Biotin Conjugated size: 0.1ml 333

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