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ATG1/ULK1 Antibody

ATG1/ULK1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameATG1/ULK1 Primary Polyclonal Antibody
Also known asATG1/ULK1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenATG1/ULK1
SpecificityThis is a highly specific antibody against ATG1/ULK1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range1004-1050/1050
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ATG1/ULK1
Gene ID number8408
Swiss ProtO75385
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, May phosphorylate ATG13/KIAA652 and RPTOR, PRKAB2 and PRKAG1, Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR, Plays a role early in neuronal differentiation and is required for granule cell axon formation, however such data need additional evidences, leading to negatively regulate AMPK activity, the precursors of autophagosomes, Serine/threonine-protein kinase involved in autophagy in response to starvation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ATG1A, Autophagy-related protein 1 homolog, KIAA722, Serine/threonine-protein kinase ULK1, ULK1, UNC51, Unc-51-like kinase 1, Unc51, hATG1, 1, ATG1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetATG1/ULK1
Short nameATG1/ULK1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameATG1/ULK1 (Antibody to)
Alternative techniqueantibodies
Identity 12558
Gene ULK1
Long gene name unc-51 like autophagy activating kinase 1
Synonyms gene name elegans) , elegans)-like kinase 1 unc-51-like kinase 1 (C, unc-51 (C
Synonyms ATG1 ATG1A
Synonyms name ATG1 autophagy related 1 homolog (S, cerevisiae)
Locus 12q24, 33
Discovery year 1998-09-03
GenBank acession AF045458
Entrez gene record 8408
Pubmed identfication 9693035
Classification Autophagy related
Havana BLAST/BLAT OTTHUMG00000168052

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