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ATG1/ULK1 Antibody, Cy3 Conjugated

ATG1/ULK1 Antibody, Cy3 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy3 Conjugated, ATG1/ULK1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenATG1/ULK1
SpecificityThis is a highly specific antibody against ATG1/ULK1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range1004-1050/1050
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human ATG1/ULK1
Gene ID number8408
Swiss ProtO75385
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, May phosphorylate ATG13/KIAA652 and RPTOR, PRKAB2 and PRKAG1, Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR, Plays a role early in neuronal differentiation and is required for granule cell axon formation, however such data need additional evidences, leading to negatively regulate AMPK activity, the precursors of autophagosomes, Serine/threonine-protein kinase involved in autophagy in response to starvation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms ATG1 ATG1A
Properties 1 of the ATG1/ULK1 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetATG1/ULK1 Conjugated
Short name Conjugated, ATG1/ULK1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, ATG1/ULK1 (Antibody to)
Alternative techniqueantibodies
Identity 12558
Gene ULK1
Long gene name unc-51 like autophagy activating kinase 1
Synonyms gene name elegans) , elegans)-like kinase 1 unc-51-like kinase 1 (C, unc-51 (C
Synonyms name ATG1 autophagy related 1 homolog (S, cerevisiae)
Locus 12q24, 33
Discovery year 1998-09-03
GenBank acession AF045458
Entrez gene record 8408
Pubmed identfication 9693035
Classification Autophagy related
Havana BLAST/BLAT OTTHUMG00000168052

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