Name : ATG1/ULK1 Antibody, Cy5.5 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN1911605440
| Long name | Cy5, 5 Conjugated, ATG1/ULK1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy5, 5, 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | ATG1/ULK1 |
| Specificity | This is a highly specific antibody against ATG1/ULK1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 1004-1050/1050 |
| Subcellular location | Cytoplasm |
| Source | KLH conjugated synthetic peptide derived from human ATG1/ULK1 |
| Gene ID number | 8408 |
| Swiss Prot | O75385 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, May phosphorylate ATG13/KIAA652 and RPTOR, PRKAB2 and PRKAG1, Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR, Plays a role early in neuronal differentiation and is required for granule cell axon formation, however such data need additional evidences, leading to negatively regulate AMPK activity, the precursors of autophagosomes, Serine/threonine-protein kinase involved in autophagy in response to starvation |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 675nm/694nm |
| Synonyms | ATG1 ATG1A |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target | ATG1/ULK1 Conjugated |
| Short name | Conjugated, ATG1/ULK1 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | 5, Cy5 |
| Alternative name | cyanine 5, 5 coupled, ATG1/ULK1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 12558 |
| Gene | ULK1 |
| Long gene name | unc-51 like autophagy activating kinase 1 |
| Synonyms gene name | elegans) , elegans)-like kinase 1 unc-51-like kinase 1 (C, unc-51 (C |
| Synonyms name | ATG1 autophagy related 1 homolog (S, cerevisiae) |
| Locus | 12q24, 33 |
| Discovery year | 1998-09-03 |
| GenBank acession | AF045458 |
| Entrez gene record | 8408 |
| Pubmed identfication | 9693035 |
| Classification | Autophagy related |
| Havana BLAST/BLAT | OTTHUMG00000168052 |