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ATG4D Antibody, ALEXA FLUOR 488

ATG4D Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, ATG4D Polyclonal Antibody
Also known asAnti-ATG4D PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenATG4D
SpecificityThis is a highly specific antibody against ATG4D
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range425-474/474
Subcellular location Mitochondrion, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ATG4D
Gene ID Number84971
Swiss ProtQ86TL0
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, Cysteine protease ATG4D, Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, Has also an activity of delipidating enzyme for the PE-conjugated forms, ROS, The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, mitochondrial: Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis, mitophagy and cell viability, to reveal a C-terminal glycine, which is necessary for autophagy, Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms APG4-D
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the ATG4D Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetATG4D
Short nameATG4D Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, ATG4D (Antibody to)
Alternative techniqueantibodies
Identity 20789
Gene ATG4D
Long gene name autophagy related 4D cysteine peptidase
Synonyms gene AUTL4 APG4D
Synonyms gene name AUT-like 4, cerevisiae) APG4 autophagy 4 homolog D (S, cerevisiae) ATG4 autophagy related 4 homolog D (S, cerevisiae) autophagy related 4D, cysteine endopeptidase (S, cysteine peptidase
Locus 19p13, 2
Discovery year 2003-04-11
GenBank acession AJ312332
Entrez gene record 84971
Pubmed identfication 12446702
RefSeq identity NM_032885
Classification Autophagy related
Havana BLAST/BLAT OTTHUMG00000180582

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