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ATIC/AICAR transformylase Antibody, ALEXA FLUOR 488

ATIC/AICAR transformylase Antibody, ALEXA FLUOR 488 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 488 Conjugated, ATIC/AICAR transformylase Antibody
Also known asAnti-ATIC/AICAR transformylase PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenATIC/AICAR transformylase
SpecificityThis is a highly specific antibody against ATIC/AICAR transformylase
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ATIC/AICAR transformylase
Gene ID Number471
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) transformylase catalyzes the second to last step in purine biosynthesis, Defects in the ATIC transformylase gene can cause AICA-rebsuria, Individuals with AICA-rebosuria accumulate AICA-riboside, Mental retardation, Patients also excrete very large amounts of AICA-riboside in the urine, also designated AICA-ribosiduria, also designated ZMP, an inborn error in purine biosynthesis that is neurologically cataclysmic, and its derivatives in erythrocytes and fibroblasts, dysmorphic features and congenital blindness are all symptoms of this disease, epilepsy, playing an important role in the production of nucleotides and IMP, The bifunctional purine biosynthesis protein ATIC (also designated PURH) contains AICAR transformylase and IMP cyclohydrolase activities
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms PURH AICARFT IMPCHASE
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the ATIC/AICAR transformylase Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetATIC/AICAR transformylase
Short nameATIC/AICAR transformylase Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, ATIC/AICAR transformylase (Antibody to)
Alternative techniqueantibodies
Identity 794
Gene ATIC
Long gene name 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Synonyms name phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
Locus 2q35
Discovery year 1997-05-15
Entrez gene record 471
Pubmed identfication 8567683 9378707
RefSeq identity NM_004044
Havana BLAST/BLAT OTTHUMG00000133023

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