| Long name | ATP5B Primary Polyclonal Antibody |
| Also known as | ATP5B PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | ATP5B |
| Specificity | This is a highly specific antibody against ATP5B |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ATP5B |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | ATP5B, ATP5B, ATP5B is encoded by a nuclear gene and assembled with the other subunits encoded by both mitochondrial and nuclear genes, ATP5B mRNA levels vary among species through transcriptional control with high expression levels in heart, ATP5C1, ATP5D and ATP5E, ATP5F1 and ATP5L, ATP5G1, ATP5G2, ATP5G3, ATP5I, ATP5J, ATP5J2, ATP5S, ATPSB or mitochondrial ATP synthetase, F1 consists of five distinct subunits, The ATP5B gene is activated by members of the Ets family of transcription factors, The two multi-subunit complexes are designated F1 and F0, also designated ATPMB, beta subunit, designated ATP5A, designated ATP5H, is a 529 amino acid protein that localizes to the mitochondrial membrane and exists as a subunit of the F0 complex, lower levels in skeletal muscle and the lowest levels in liver and kidney, suggesting that Ets transcription factors are involved in the enhanced expression of the ATP5B gene in highly proliferating cells and in the coordinate transcription of nuclear genes for mitochondrial proteins, the former of which comprises the soluble catalytic core and the latter of which comprises the membrane-spanning proton channel of ATP synthase, while F0 consists of ten subunits, Mitochondrial ATP synthase is composed of two multi-subunit complexes that utilize an inner membrane electrochemical gradient to catalyze the synthesis of ATP during oxidative phosphorylation |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ATP Synthase H+ Transporting Mitochondrial F1 Complex Subunit Beta, ATP synthase H+ transporting mitochondrial F1 complex beta polypeptide, ATP synthase subunit beta, ATP synthase subunit beta mitochondrial, ATP5B, ATPB, ATPB_HUMAN, ATPMB, ATPSB, MGC5231, Mitochondrial ATP Synthase Subunit Beta, Mitochondrial ATP synthase beta subunit, Mitochondrial ATP synthetase beta subunit, mitochondrial, ATP 5B |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | ATP5B |
| Short name | ATP5B Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | H+ transporting, b polypeptide (Antibody to), mitochondrial F1 complex, adenosine triphosphate synthase |
| Alternative technique | antibodies |
| Alternative to gene target | ATP5B and IDBG-41395 and ENSG00000110955 and 506, ATP5B and IDBG-635890 and ENSBTAG00000013315 and 327675, ATPMB and ATPSB and HEL-S-271, Atp5b and IDBG-196497 and ENSMUSG00000025393 and 11947, H+ transporting, acting on acid anhydrides, acting on acid anhydrides, acting on acid anhydrides, beta polypeptide, catalytic core F(1) and cellular component this GO :0046034 and ATP metabolic process and biological process this GO :0046933 and proton-transporting ATP synthase activity, catalytic core and cellular component this GO :0005759 and mitochondrial matrix and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006091 and generation of precursor metabolites and energy and biological process this GO :0006200 and ATP catabolic process and biological process this GO :0006629 and lipid metabolic process and biological process this GO :0006754 and ATP biosynthetic process and biological process this GO :0006933 and negative regulation of cell adhesion involved in substrate-bound cell migration and biological process this GO :0009986 and cell surface and cellular component this GO :0015986 and ATP synthesis coupled proton transport and biological process this GO :0015991 and ATP hydrolysis coupled proton transport and biological process this GO :0015992 and proton transport and biological process this GO :0016020 and membrane and cellular component this GO :0016820 and hydrolase activity, catalytic domain and cellular component this GO :0042288 and MHC class I protein binding and molecular function this GO :0042645 and mitochondrial nucleoid and cellular component this GO :0042776 and mitochondrial ATP synthesis coupled proton transport and biological process this GO :0044237 and cellular metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045261 and proton-transporting ATP synthase complex, catalyzing transmembrane movement of substances, catalyzing transmembrane movement of substances and also this GO :0016887: ATPase activity and also this GO :0017111: nucleoside-triphosphatase activity and also this GO :0022857: transmembrane transporter activity and also this GO :0042288: MHC class I protein binding and also this GO :0046933: proton-transporting ATP synthase activity, catalyzing transmembrane movement of substances and molecular function this GO :0016887 and ATPase activity and molecular function this GO :0017111 and nucleoside-triphosphatase activity and molecular function this GO :0022857 and transmembrane transporter activity and molecular function this GO :0022904 and respiratory electron transport chain and biological process this GO :0031966 and mitochondrial membrane and cellular component this GO :0033178 and proton-transporting two-sector ATPase complex, hydrolase activity, mitochondrial F1 complex, nuclei, rotational mechanism, rotational mechanism, rotational mechanism, rotational mechanism and also this GO :0046961: proton-transporting ATPase activity, rotational mechanism and molecular function this GO :0046961 and proton-transporting ATPase activity, rotational mechanism and molecular function this GO :0051453 and regulation of intracellular pH and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0001525 and angiogenesis and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0005215 and transporter activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005743 and mitochondrial inner membrane and cellular component this GO :0005753 and mitochondrial proton-transporting ATP synthase complex and cellular component this GO :0005754 and mitochondrial proton-transporting ATP synthase, this GO :0005215: transporter activity, this GO :0005215: transporter activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016820: hydrolase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016820: hydrolase activity, this GO :0016887: ATPase activity, this GO :0017111: nucleoside-triphosphatase activity, this GO :0022857: transmembrane transporter activity, this GO :0042288: MHC class I protein binding, this GO :0046933: proton-transporting ATP synthase activity, this GO :0046961: proton-transporting ATPase activity, ATP synthase |
| Identity | 830 |
| Gene | ATP5B |
| Long gene name | ATP synthase, H+ transporting, beta polypeptide , mitochondrial F1 complex |
| Synonyms gene | ATPSB |
| Locus | 12q13, 3 |
| Discovery year | 1989-06-30 |
| GenBank acession | M27132 |
| Entrez gene record | 506 |
| Pubmed identfication | 2687158 |
| RefSeq identity | NM_001686 |
| Classification | F-type ATPases Mitochondrial complex V: ATP synthase subunits |
| Havana BLAST/BLAT | OTTHUMG00000170291 |
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