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ATRIP (Ser68+Ser72) Antibody

ATRIP (Ser68+Ser72) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameATRIP (Ser68+Ser72) Primary Polyclonal Antibody
Also known asATRIP (Ser68+Ser72) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenATRIP Ser68+Ser72
SpecificityThis is a highly specific antibody against ATRIP Ser68+Ser72
Modification(s)Phosphorylation
Modification site(s)Ser68+Ser72
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human ATRIP around the phosphorylation site of Ser68 + Ser72 [LA(p-S)QAL(p-S)QC]
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen ATM and ATR kinases are important for cell cycle checkpoint response signalling, ATR-interacting protein (ATRIP), ATRIP is a nuclear protein that may also play a role in protein stabilization, ATRIP is a ubiquitously expressed protein that can form heterodimers with ATR, After dimerization they bind the RPA complex and are recruited to single stranded DNA, Checkpoint proteins include Rad17, Chk2, In response to DNA damage, It is also important for ATR expression, Rad1, Rad9 and Hus1, also designated ATM and Rad3-related-interacting protein, is required for checkpoint signaling after DNA damage, which are involved in regulating cell cycle arrest at the G2 checkpoint, which is involved in regulating cell cycle progression at the G1 checkpoint as well as Chk1, which regulates DNA replication and damage checkpoint responses, DNA damage or incomplete replication of DNA results in the inhibition of cell cycle progression at the G1 to S or the G2 to M phase transition by conserved regulatory mechanisms known as cell cycle checkpoints
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 3' repair exonuclease 1, 3'-5' exonuclease TREX1, AGS 1, AGS-1, AGS1, ATIP, ATM and Rad3 related interacting protein, ATM and Rad3-related-interacting protein, ATR interacting protein, ATR-interacting protein, ATRIP Ser68 + Ser72, ATRIP_HUMAN, Aicardi Goutieres syndrome 1, Atrip, DKFZp434J0310, DKFZp762J2115, DNase III, DRN 3, DRN3, Deoxyribonuclease III dnaQ/mutD E, FLJ12343, MGC20625, MGC21482, MGC26740, P-ATRIP Ser68/Ser72, TREX 1, TREX1, TREX1 protein, Three prime repair exonuclease 1, coli like, ATRIP phospho S68 + S72
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetATRIP (Ser68+Ser72)
Short nameATRIP (Ser68+Ser72) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameATRIP (Ser68+Ser72) (Antibody to)
Alternative techniqueantibodies
Identity 33499
Gene ATRIP
Long gene name ATR interacting protein
Synonyms FLJ12343 MGC20625 MGC21482 MGC26740
Locus 3p21, 31
Discovery year 2007-06-20
GenBank acession AF451323
Entrez gene record 84126
Pubmed identfication 11721054
RefSeq identity NM_130384
Havana BLAST/BLAT OTTHUMG00000133532

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