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ATRIP (Ser68+Ser72) Antibody, Biotin Conjugated

ATRIP (Ser68+Ser72) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, ATRIP (Ser68+Ser72) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenATRIP Ser68+Ser72
SpecificityThis is a highly specific antibody against ATRIP Ser68+Ser72
ModificationPhosphorylation
Modification siteSer68+Ser72
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human ATRIP around the phosphorylation site of Ser68 + Ser72 [LA(p-S)QAL(p-S)QC]
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background ATM and ATR kinases are important for cell cycle checkpoint response signalling, ATR-interacting protein (ATRIP), ATRIP is a nuclear protein that may also play a role in protein stabilization, ATRIP is a ubiquitously expressed protein that can form heterodimers with ATR, After dimerization they bind the RPA complex and are recruited to single stranded DNA, Checkpoint proteins include Rad17, Chk2, In response to DNA damage, It is also important for ATR expression, Rad1, Rad9 and Hus1, also designated ATM and Rad3-related-interacting protein, is required for checkpoint signaling after DNA damage, which are involved in regulating cell cycle arrest at the G2 checkpoint, which is involved in regulating cell cycle progression at the G1 checkpoint as well as Chk1, which regulates DNA replication and damage checkpoint responses, DNA damage or incomplete replication of DNA results in the inhibition of cell cycle progression at the G1 to S or the G2 to M phase transition by conserved regulatory mechanisms known as cell cycle checkpoints
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms FLJ12343 MGC20625 MGC21482 MGC26740
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetATRIP (Ser68+Ser72) Conjugated
Short name Conjugated, ATRIP (Ser68+Ser72) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, ATRIP (Ser68+Ser72) (Antibody to)
Alternative techniqueantibodies
Identity 33499
Gene ATRIP
Long gene name ATR interacting protein
Locus 3p21, 31
Discovery year 2007-06-20
GenBank acession AF451323
Entrez gene record 84126
Pubmed identfication 11721054
RefSeq identity NM_130384
Havana BLAST/BLAT OTTHUMG00000133532

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