ATRIP/TREX1 Antibody

ATRIP/TREX1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 263

Size 0.1ml

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Long name	ATRIP/TREX1 Primary Polyclonal Antibody
Also known as	ATRIP/TREX1 PAb
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	ATRIP/TREX1
Specificity	This is a highly specific antibody against ATRIP/TREX1
Modification(s)	None
Modification site(s)	Unmodified antibody
Clonality	Polyclonal antibody
Clone number	Polyclonal antibody
Concentration	1ug per 1ul
Source	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ATRIP
Tested Applications	IF(IHC-P), IHC-P, WB
Recommended dilutions	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity	Mouse, Rat, Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	ATM and ATR kinases are important for cell cycle checkpoint response signalling, ATR-interacting protein (ATRIP), ATRIP is a nuclear protein that may also play a role in protein stabilization, ATRIP is a ubiquitously expressed protein that can form heterodimers with ATR, After dimerization they bind the RPA complex and are recruited to single stranded DNA, Checkpoint proteins include Rad17, Chk2, In response to DNA damage, It is also important for ATR expression, Rad1, Rad9 and Hus1, also designated ATM and Rad3-related-interacting protein, is required for checkpoint signaling after DNA damage, which are involved in regulating cell cycle arrest at the G2 checkpoint, which is involved in regulating cell cycle progression at the G1 checkpoint as well as Chk1, which regulates DNA replication and damage checkpoint responses, DNA damage or incomplete replication of DNA results in the inhibition of cell cycle progression at the G1 to S or the G2 to M phase transition by conserved regulatory mechanisms known as cell cycle checkpoints
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	3' repair exonuclease 1, 3'-5' exonuclease TREX1, AGS-1, AGS1, ATIP, ATM and Rad3 related interacting protein, ATM and Rad3-related-interacting protein, ATR interacting protein, ATR-interacting protein, ATRIP_HUMAN, Aicardi Goutieres syndrome 1, Atrip, DKFZp434J0310, DKFZp762J2115, DNase III, DRN 3, DRN3, Deoxyribonuclease III dnaQ/mutD E, FLJ12343, MGC20625, MGC21482, MGC26740, TREX 1, TREX1, TREX1 protein, Three prime repair exonuclease 1, coli like, AGS 1
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target	ATRIP/TREX1
Short name	ATRIP/TREX1 Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	ATRIP/TREX1 (Antibody to)
Alternative technique	antibodies
Identity	33499
Gene	ATRIP
Long gene name	ATR interacting protein
Synonyms	FLJ12343 MGC20625 MGC21482 MGC26740
Locus	3p21, 31
Discovery year	2007-06-20
GenBank acession	AF451323
Entrez gene record	84126
Pubmed identfication	11721054
RefSeq identity	NM_130384
Havana BLAST/BLAT	OTTHUMG00000133532

ATRIP/TREX1 Antibody

ATRIP/TREX1 Antibody size: 0.1ml 263

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