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ATX2 Antibody, FITC Conjugated

ATX2 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, ATX2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenATX2
SpecificityThis is a highly specific antibody against ATX2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range770-820/1313
SourceKLH conjugated synthetic peptide derived from human ATX2
Gene ID number6311
Swiss ProtQ99700
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background ADCA has been divided into three groups: ADCA types I-III, ATX2 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, ATX2 is caused by expansion of a CAG repeat in the coding region of ATX2, Clinically, Longer expansions result in earlier onset of the disease, There are four named isoforms, brain stem and spinal cord, bulbar and extrapyramidal signs, ophthalmoplegia, peripheral neuropathy and dementia, The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms ATX2
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetATX2 Conjugated
Short name FITC Conjugated, ATX2 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, ATX2 (Antibody to)
Alternative techniqueantibodies
Identity 10555
Gene ATXN2
Long gene name ataxin 2
Synonyms gene SCA2 TNRC13
Synonyms gene name ataxin 2) , autosomal dominant, spinocerebellar ataxia 2 (olivopontocerebellar ataxia 2
Synonyms name trinucleotide repeat containing 13
Locus 12q24, 12
Discovery year 1991-08-06
GenBank acession U80749
Entrez gene record 6311
Pubmed identfication 8358438 9225980
RefSeq identity NM_002973
Classification Ataxins Trinucleotide repeat containing
Havana BLAST/BLAT OTTHUMG00000133475
Locus Specific Databases LRG_864

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