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ATXN1 (Ser775) Antibody, FITC Conjugated

ATXN1 (Ser775) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, ATXN1 (Ser775) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenATXN1 Ser775
SpecificityThis is a highly specific antibody against ATXN1 Ser775
ModificationPhosphorylation
Modification siteSer775
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human Ataxin-1 around the phosphorylation site of Ser775
Gene ID number6310
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background 2, 3, 4 and 6, ADCA has been divided into three groups: ADCA types I-III, ADCA is caused by the expansion of the CAG repeats, ADCAI is genetically heterogeneous, ADCAII, At least two transcript variants encoding the same protein have been found for this gene, Clinically, Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions, The expanded repeats are variable in size and unstable, The function of the ataxins is not known, This locus has been mapped to chromosome 6, [provided by RefSeq], and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), and is associated with spinocerebellar ataxia type 1 (SCA1), and it has been determined that the diseased allele contains41-81 CAG repeats, are most likely homogeneous disorders, being assigned to five different chromosomes, brain stem and spinal cord, compared to 6-39 in the normal allele, designated spinocerebellar ataxia (SCA) 1, producing an elongated polyglutamine tract in the corresponding protein, usually increasing in size when transmitted to successive generations, which always presents with retinal degeneration (SCA7), with five genetic loci, The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms D6S504E ATX1
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetATXN1 (Ser775) Conjugated
Short name FITC Conjugated, ATXN1 (Ser775) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, ATXN1 (Ser775) (Antibody to)
Alternative techniqueantibodies
Identity 10548
Gene ATXN1
Long gene name ataxin 1
Synonyms gene SCA1
Synonyms gene name ataxin 1) , autosomal dominant, spinocerebellar ataxia 1 (olivopontocerebellar ataxia 1
Locus 6p22, 3
Discovery year 1986-01-01
GenBank acession X79204
Entrez gene record 6310
Pubmed identfication 1582256
RefSeq identity NM_000332
Classification Ataxins
Havana BLAST/BLAT OTTHUMG00000014303
Locus Specific Databases LRG_863

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